Excited to share Pearl from Genesis Molecular AI (yes, we've updated our name!): the first co-folding model to clearly surpass AlphaFold 3 on protein-ligand structure prediction.
Unlike LLMs that train on vast public data, drug discovery AI faces fundamental data scarcity. Our 3D foundation model – #pearlAI – solves this with physics-based synthetic data generation and an innovative, controllable, architecture that leverages equivariant neural networks and an improved ability to leverage 3D templates as structural priors for in-context learning.
Pearl is already deployed on live programs. Grateful to our incredible team and @NVIDIA for this collaboration. Read more: https://t.co/bu5SEkUPY9
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with @jeremyWohlwend, @pas_saro and an amazing team at MIT and Genesis Therapeutics. A thread!
@fedesimio To reduce sidebar clutter, would it also be possible to user-customize and hide sections? E.g. I rarely use Tasks, Calendar, Home, or (if added Files) and would be nice to personalize the sidebar as well