Daniel Coakley

Sustainability Manager at Lloyds Banking Group

[Daniel Coakley @decoakley]

@DeItaone NO, U.S. ASSETS WERE STRUCK!

[Daniel Coakley @decoakley]

@grok @hafizabubkr @NoLimitGains Can you pair this with broader context as you mentioned (rates, earnings, sentiment etc) and analyse the level of risk vs potential returns

[Daniel Coakley @decoakley]

@TheRabbitHole @elonmusk @vkhosla @Tesla @SpaceX @X @grok is this chart misleading?

[Daniel Coakley @decoakley]

@chen66181384 @elonmusk @LinkN01 @grok Use realistic assumptions for Boeing 737, Ryanair's average flight distance, Starlink antenna specs, fuel costs and any other relevant inputs to work out the actual impact on fuel cost per mile flown

[Daniel Coakley @decoakley]

@Ant0nLindgren @Bicep_crypto https://t.co/7rmBCfJnkp

[Daniel Coakley @decoakley]

@adamfeuerstein Is this significant for $NTLA ahead of #FDA letter? I just noticed on the https://t.co/fWRMfCvBLj website, that an update was made to the number of trial participants from 765 to 1200 in an update posted on 24 November, well after the clinical hold. @GeneInvesting positive sign?

[Daniel Coakley @decoakley]

@OctavianSiiu @GeneInvesting https://t.co/7rmBCfIPuR I think an FDA hold lift is coming soon. All biotech is rallying, but $ntla looking more bullish

[Daniel Coakley @decoakley]

@adamfeuerstein Is this significant for $NTLA ahead of #FDA letter? I just noticed on the https://t.co/fWRMfCvBLj website, that an update was made to the number of trial participants from 765 to 1200 in an update posted on 24 November, well after the clinical hold. @GeneInvesting positive sign?

[Daniel Coakley @decoakley]

@KlausMolle @adamfeuerstein @GeneInvesting Thanks I just saw that in the Q2 update. Still seems promising that the study information is actively being updated as of 2 weeks ago. Also current job postings by NTLA suggest they are recruiting for commercial product launch, although perhaps this is just HAE

[Daniel Coakley @decoakley]

@adamfeuerstein @GeneInvesting In the same update, they also removed some recruiting series in South Korea and Australia, but the rest are unchanged. Looks positive for a trial that's likely to resume, but based on an expanded population in response to FDA request for safety profile.

[Daniel Coakley @decoakley]

@adamfeuerstein Is this significant for $NTLA ahead of #FDA letter? I just noticed on the https://t.co/fWRMfCvBLj website, that an update was made to the number of trial participants from 765 to 1200 in an update posted on 24 November, well after the clinical hold. @GeneInvesting positive sign?

[Daniel Coakley @decoakley]

@grok @JosephSarnecki @MarioNawfal What would long term brain impact studies be required if the therapy doesn't cross the blood brain barrier and as you've stated brain cholesterol isn't directly affected by peripheral levels?

[Daniel Coakley @decoakley]

@grok @JosephSarnecki @MarioNawfal What about the blood brain barrier? Does this therapy impact cholesterol in the brain?

[Daniel Coakley @decoakley]

@JosephSarnecki @MarioNawfal @grok can you comment on this in the context of crispr ctx310 trial. Is this a valid concern?

[Daniel Coakley @decoakley]

@GeneInvesting Nice coverage in Time today also: Can a One-Time Gene Therapy Lower Cholesterol? | TIME https://t.co/FZ7KReykz5

[dave ❄️ 🥕 🧻 @mrdavemacleod]

the two things that convince me that this is a Nazi salute are:

1. It’s exactly like a Nazi salute
2. Elon Musk is a bit of a Nazi

[Led By Donkeys @ByDonkeys]

This is who @ElonMusk really is. Don’t buy a Tesla.

Location: Tesla European HQ, Amsterdam.

[Daniel Coakley @decoakley]

Pretty low standard for Trump's right hand man. 😬

[Elon Musk @elonmusk]

@joni_askola F u retard

[Daniel Coakley @decoakley]

@PeterSchiff At least someone is talking sense. It's amazing how the voice of reason seems to have been drowned out on social media platforms over the last few years. It's almost as if the wealthy elite that control it have some sort of hidden agenda 🤔

[Daniel Coakley @decoakley]

@WallStreetMav These are marginal rates of tax for the highest portion of your earnings, IF you earn a sufficiently high salary. There are also many ways to reduce your tax burden, such as contributing to your pension in the UK. But I guess that doesn't grab enough attention eh 🙄

[Daniel Coakley @decoakley]

@uxaiagency @grok @xai Also, I've never found ChatGPT to give a politically biased response, and it generally avoids doing so, even when specifically requested. Here's a link to a chat where I asked for an opinion on same. Were you using standard or altered settings? https://t.co/noU4vj0Eq3

[Daniel Coakley @decoakley]

@uxaiagency @grok @xai Looks like it just contradicted itself in the subsequent clarifications though? The corrections and clarifications seem like semantics rather than factual inaccuracies. The original prompt asked for an opinion, which is what has been given in response.