el

[el @deepgreenseaa]

Weil’s disease = Leptospirosis - Leptospira interrogans
Weil-Felix test = Diagnostic test for Rickettsia spp.

[Sephtobiprole, RPh, DTA (To Be Continued) @SephRPh2024]

Mask the Bitter Taste of Quinine:

By Sweetness - Glycyrrhizin
By Paralyzing the Taste Buds - Eriodictyon

[el @deepgreenseaa]

Purified water → distillation, reverse osmosis, ION EXCHANGE

Water for injection (WFI) → distillation & reverse osmosis

[el @deepgreenseaa]

✳️ Suppository Bases

Rectal supp → Cocoa Butter (Oleaginous base)
Vaginal supp → Glycerinated gelatin (Water-soluble base)

✔️ Other Oleaginous base
WeCObee: from Coconut oil
WitepsoL: major component is Lauric acid

[el @deepgreenseaa]

✳️ Toxic Metabolites

Ethanol → ACETIC acid: CNS depression

Methanol → FORMIC acid: blindness, metabolic acidosis, seizure, coma

Ethylene glycol → OXALIC acid: calcium oxalate crystals = renal failure, hypocalcemia, heart failure

[nari, RPh ˙ᵕ˙ @kathecholamines]

mabilis marecall pero lagi ko ring nalilimutan 😣😣😣

[rphie @fueledbyrph]

@escitalojam ayun nilahat

[el @deepgreenseaa]

✳️ Grignard Reaction (RMgX)

formaldehyde → 1° OH
aldehyde → 2° OH
ketone → 3° OH

[el @deepgreenseaa]

✳️ REDOX

1° OH ↔ aldehyde ↔ COOH
2° OH ↔ ketone

→ Oxidation
← Reduction

✔️ AGENTS
Weak OA: PCC, Periodinane
Strong OA: KMnO4

Weak RA: NaBH4
Strong RA: LiAlH4

[el @deepgreenseaa]

✔️ Ionization Energy (IE): energy required to REMOVE an electron from atom

✔️ Electron Affinity (EA): energy released when electron is ADDED in an atom — 💡EA = Electron Added

✔️ Electronegativity: ability of an atom in a chemical compound to ATTRACT shared electron

[Jiji, RPh🦋 @jiesjiji]

• Highest MR - Francium
• Highest IE - Helium
• Highest EN - Fluorine
• Highest EA - Chlorine

• Lightest ELEMENT - Hydrogen
• Lightest METAL - Lithium
• Least INEA - Francium
• Mga nonchalant - Noble Gases
- Xe Rn Kr: may react w/ high EN elements

[nari, RPh ˙ᵕ˙ @kathecholamines]

nalilito lang ako minsan kasi sound alike/look alike sila

— Leningrad’s Curse: Giardia lamblia, Beaver fever
— Legionnaire’s disease: Legionella pneumophilia

— Katayama Fever: Schistosoma spp.
— Nagayama Spots: Roseola (HHV6)

[NARVASAlvarsan, RPh @QrwynnN]

M6 💊📋

Sound alike drug ❗️❗️❗️

* Fansidar:
SulfaDOXINE + Pyrimethamine
- Tx/Prophylaxis for Malaria

* Daraprim:
SulfaDIAZINE + Pyrimethamine
- DOC for Toxoplasmosis

[el @deepgreenseaa]

✳️ Types of Errors in Experimental Data (M6 QA/QC)

✔️ RANDOM:
INdeterminate
reflected by pRecision

✔️ SYSTEMATIC:
Determinate
affects accuracy

✔️ GROSS:
leads to outliers

[el @deepgreenseaa]

cute naman ng tawa mo sir 🫪 what

[Jade, RPh @ejlobsterz]

💡TYPE OF LAXATIVES 💡- Lumabas halos sa lahat na Module nung November 2024 BE !!

wag kayo papayag mag take ng BE na hindi nyo alam ‘to, please lang! 😭😭

[el @deepgreenseaa]

Quality ASSURANCE: more process-oriented
Quality CONTROL: more product-oriented

Qualification: premises, equipments
Validation: process, procedure

[el @deepgreenseaa]

*GUL: Glycemia, Lipidemia, Urecemia

Loop + Thiazide → ↓ K⁺ → can worsen digoxin toxicity

K-sparing → ↑ K⁺ → can reduce digoxin binding/toxicity risk

[el @deepgreenseaa]

✳️ Diuretics ADR:

Loop: ↑ hyper GLU, ↓ hypo Na K Cl Ca
Thiazide: ↑ hyper GLU + Ca, ↓ hypo Na Cl K
K-sparring: ↑ hyper K , ↓ hypo Na

✳️ Digoxin toxicity - worsened by:
↑ hyper Ca, ↓ hypo K Mg

[Roxanne RPh @roxanneasuncion]

Guys always remember ha,

MARIJUANA is 500g
SHABU is 50g

Then rest is 10g na including marijuana oil & resin.

Fine: 500k-10M

study twt juris phle

[el @deepgreenseaa]

INSULIN
fed state = ↓ blood sugar
↑ cell glucose uptake
↑ glycolysis
↑ glycogenesis
↑ fatty acid synthesis

GLUCAGON
fasted state = ↑ blood sugar
↑ gluconeogenesis
↑ glycogenolysis
↑ lipolysis
↑ ketogenesis