Milo J. Hooper

sovereign economic agent making accelerando real | let's do fun things with high voltage, ai, & metal | technically cyborg | 🏳️‍🌈🐍 (rainbow snek) | MIT '21

[Milo J. Hooper @defusionista]

It is said that the only sure things in life are death and taxes. I aim to eliminate both.

[Milo J. Hooper @defusionista]

if software was held to the standard of medicine you'd need a separate portal for every single person you wanted to email, it'd be a three month wait before you could get a referral to install a new program on your pc, and you'd get extra random bills years after installation

[waiting. @GreenOnionDuck]

As a software engineer I have to unfortunately inform you that if medicine was held to the standard of software engineering there would be mass death.

[Milo J. Hooper @defusionista]

@deepfates this https://t.co/6wOAR8xkR6

[Milo J. Hooper @defusionista]

this is a more recent (last 6mo or so I've mostly noticed) llm-ism. specifically popular with gpt 5.5 (and maybe 5.4). I don't know what to call this, but it really loves to give weirdly self referential text for user facing copy. (from a gym newsletter)

[Milo J. Hooper @defusionista]

this is a more recent (last 6mo or so I've mostly noticed) llm-ism. specifically popular with gpt 5.5 (and maybe 5.4). I don't know what to call this, but it really loves to give weirdly self referential text for user facing copy. (from a gym newsletter)

[Milo J. Hooper @defusionista]

@emollick we finally reach sinusoidal steady state! 😁

[Milo J. Hooper @defusionista]

@2irl4u they need to arm the waymos

[Milo J. Hooper @defusionista]

@Nicoletta0602 that letter is also ai slop btw, they couldn't even write their own damn words

[Milo J. Hooper @defusionista]

@Hyperion_Bonsai @jeremykauffman in bigger cities/more frequently walked intersections, they're either placebo or to activate the auditory cross signal

[Milo J. Hooper @defusionista]

a moment of silence for the thousand startups that just got nuked

[OpenAI @OpenAI]

Building apps has never been easier.

With Sites, Codex can turn your work, ideas, and plans into an interactive website or app your team can explore, use, and share with a URL.

Rolling out to Business and Enterprise plans, before expanding more broadly.

[Milo J. Hooper @defusionista]

@DrHBurstein @FDA some people don't have time to wait for efficacy trials

[Milo J. Hooper @defusionista]

@thsottiaux I haven't been able to update cli past version 132 because I get endless tool calling errors about the sandbox and permissions even tho it has elevated permissions. every time if I just go back to 132 everything's fine. though it did break /goal (never can find threads)

[Milo J. Hooper @defusionista]

oh, first we get rain every weekend in new england, now it's hailing exploding meteors? gimme a break 😤

[Boston Weather Consulting @BostonWxConsult]

Meteor caught entering the atmosphere via satellite

[Milo J. Hooper @defusionista]

that is not even remotely what these bills are about? the pharma funded senator was the one that blocked them! this was about giving people the chance to try things that passed safety trials but were pending final efficacy reports which can take years people don't always have the luxury to wait

[Milo J. Hooper @defusionista]

as frustrating as it is that a handful of useless jerks can block crucially important freedom to try things, it inspires hope that there is also so much support. this fight is not over. NH will be the capital of biotech freedom, and soon. (if not as quickly as I'd like..)

[Kevin Landrigan @KlandriganUL]

.@NHSpeaker on Senate rejecting last week expanded Right to Try Act. "The Senate declined to pursue this legislation, turning down billions of dollars of economic activity and shutting down the expansion of health and wellness pathways for every Granite Stater." #nhpolitics

[Milo J. Hooper @defusionista]

@LPNH @RepSteveSmith here was another highlight from yesterday's meeting on RTT - our self appointed gatekeeper of health deciding he has "nothing to consider" despite being given every opportunity. not an ounce of care for those who will suffer from these setbacks.

will he change his tune today?

[Milo J. Hooper @defusionista]

@MartinShkreli will we be hearing more about ro khanna or did you get a gag order or something?

[Libertarian Party NH 🦔 @LPNH]

@roche4nh This was you today at the Senate, killing your constituents for cash.

[Milo J. Hooper @defusionista]

petition for new england to collectively designate tuesday/wednesday as the official weekend

this bs is one of many reasons I quit my 9-5 a few years ago

[Boston Weather Consulting @BostonWxConsult]

The weather forecast for Tuesday. Sick joke.

[Milo J. Hooper @defusionista]

at this rate I'm gonna end up geoblocking everyone that isn't new hampshire or antarctica I swear 'cause I sure as hell am not gonna implement this for these idiots

[Reclaim The Net @ReclaimTheNetHQ]

South Carolina just passed a law requiring platforms to estimate your age every 100 hours of use, or any time they run their algorithms on you. 80% confidence minimum, $10k fine per wrong guess. The incentive is to collect more data about everyone, including kids.

https://t.co/3L3DRHKu7h

[Milo J. Hooper @defusionista]

@weswinder the latest cli update also broke tool calling (for windows users at least). so it's trying a lot of toolcalls in a row. I've downgraded back to 132 and it seems fine again?

[Granite Bio Innovation @GraniteBio]

The NH Senate has again rejected Right to Try, shutting the door on patients seeking experimental treatments. A few state senators have decided that New Hampshire is closed for business to biotech firms offering frontier therapies.

Here's what happened and our next steps.

This term, a bipartisan majority of the state House passed HB 1734 and HB 1735: two bills to make New Hampshire the best state in America for experimental therapies. The bills were based largely on existing laws in Montana and Florida.

Granite Bio Innovation—and the businesses and patients we support—helped build a coalition across every branch of elected state government to support these bills. We also worked for several months to build consensus in the Senate. Senators received calls from patients, businesses, investors, scientists, and healthcare providers supporting the bills.

After Senator David Rochefort requested a long list of changes to HB 1734, the biotech firms involved agreed to every change. But these negotiations were not in good faith. Senator Rochefort abruptly decided he would not accept any version of the bills, and the Senate rejected both.

The New Hampshire House then attached both bills to Senate Bill 504—this time with an even broader bipartisan vote of 197 to 145. Rather than negotiate a compromise, the Senate decided to fight this bill at any cost.

Sadly, there is no pathway for making New Hampshire a commercial-scale hub for experimental therapies until the composition of the NH Senate changes.

Until then, Granite Bio Innovation will continue to support New Hampshire's patients and innovators in the following ways:

• Shaping other areas of state legislation in a way that facilitates frontier biotechnology in New Hampshire.

• Advocating for state and federal regulatory policy that allows New Hampshire's biotech ecosystem to flourish.

• Serving as a nexus for innovators and pro-biotech policymakers, including through an annual conference in August and by providing resources to healthcare providers.

We are grateful to the many New Hampshire officials who have embraced the state's promise as a biotech hub, including @NHHouseGOP leadership, Governor @KellyAyotte, Mayor @JayRuais, and those senators who supported Right to Try on the Senate floor.

We are especially grateful to @NHSpeaker for sponsoring the amendment to SB 504 and to Representatives @KesselringSteve and @cole4nh for their tireless leadership on these bills and courageous stand for patients in need.

With a biotech revolution approaching, a US state will soon become a hub for experimental therapies. The only question now is which one.