“... we observed a high frequency of somatic mutations in patients with [acquired aplastic anemia] at baseline that appeared even more pronounced after [immunosuppressive therapy], irrespective of response status and use of eltrombopag.” Learn more: https://t.co/OuYlNof2Ev
In a phase 3 trial of aplastic anemia, clonal hematopoiesis was detected in 30% of patients at baseline and in ~80% at 24 months. The number of mutations per patient also appeared to increase over time. Full trial results: https://t.co/OuYlNof2Ev
Our work is now published in NEJM Evidence.
Excited to share our latest study on clonal hematopoiesis in aplastic anemia.
In this phase 3 randomized trial, longitudinal genomic analyses were performed at baseline, 6 months, and 24 months. https://t.co/9WZDLYkwfc
🚀 We’re looking for a Research Associate in Bioinformatics at the University of Manchester!
This is an exciting opportunity to join our team within the Next Generation Phenotyping and Diagnostics theme.
🔗 Full details and how to apply: https://t.co/ToVcQsSHSo
🎉 International Day of Women and Girls in Science ♀️
Today we’re celebrating all the inspiring women at Manchester BRC who are driving health improvements and lasting change for all through research 🔬🧬
The power of data and algorithms for health science 💻
Five Manchester BRC bioinformaticians have shared what they learned from the European Conference on Computational Biology and how they will apply this to their research projects.
✍️Read their blog 👇
https://t.co/LewFYujYv3
In the vast expanse of the universe, where lethal star radiation and near-total darkness prevail, the existence of life seems improbable. In https://t.co/49zdW4bxBY we investigate how #microorganisms on #ISS adapt to extreme conditions @Tomasz_Lab @NASAJPL@MCB_UJ@SanoScience
Happy birthday to Marie Skłodowska Curie, who was born on this day in 1867!
Marie Curie was the first person to be awarded the Nobel Prize twice, and is still the only individual to receive the prize in two different science categories.
Find out more: https://t.co/C00oKYwxxL
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
Our knowledge of human genetics drives successful drug discovery, but the median time between target discovery and drug approval has been 25 years.
A new review @Nature
https://t.co/02XhCeXbtD @KaterinaTrajan1@KaterinaTrajan1
BREAKING NEWS:
The 2020 #NobelPrize in Physiology or Medicine has been awarded jointly to Harvey J. Alter, Michael Houghton and Charles M. Rice “for the discovery of Hepatitis C virus.”