We just published in @TheLancetOncol a very important paper regarding the new FDA guidance on overall survival assessment in cancer drug trials. Right in time for #ESMO25. Please do read. I promise you that you’ll learn something that’s applicable broadly. And follow along this thread for a broader discussion of the points we make in this paper.
https://t.co/39pY771vya
Science is only valuable if it touches the patient's life.
To be clinically significant means: does it really benefit them?
Being patient-centered means: accompanying their body, their fear, their hope, their dignity.
Otherwise, all data, all words are just noise…
Congrats to oncology trainee Mary O’Reilly presenting data from her PhD on early onset colorectal cancer at ESMO GI 2025 @myESMO@RayMcDermott1@graokane@svuh
Honored to represent @UHN and @PMCancerCentre at #AATS2025. Our ctDNA Lung DETECT Study adds to the growing evidence supporting the utility of ctDNA in early-stage NSCLC #AATS25#AATS#ctDNA
Announcing a new trial in 5 Irish hospitals (& sponsored by @CancerTrials_ie) for up to 80 🇮🇪 patients. SHAMROCK will assess the effectiveness of a single treatment (T-Dxd) pre-surgery for patients with early stage HER-2 positive breast cancer.
https://t.co/1TLh1lzqws
👏Prof Bryan Hennessy & CTI team & everyone involved in bringing this new treatment option to 🇮🇪 patients.
#CancerResearch #ClinicalTrials #BreastCancerAwareness
Delighted to publish this first comprehensive multi-stakeholder expert consensus paper on definitions of irAE, by:
- natural hx
- patterns of irAE
- steroid responsiveness
Incorporates academia, nursing, pharma & regulators
Thanks @sitcancer!
@CancerCentreIre@hopkinskimmel
Pleased to publish the EGFRmt subgrp analysis of PACIFIC: Durvalumab post ChemoRT in Stage III NSCLC @JTOonline
- 35pts (durva=24 pbo=11)
- mPFS 11.2 v 10.9m
- mOS 46.8 v 43m HR 1.02
No clear benefit but also no clear harm, await LAURA trial results https://t.co/Gi04sV9AUO
Twelve days after the first shot of Pfizer’s vaccine, vaccinated people who got infected with the coronavirus carried less virus in their bodies than unvaccinated people, a study shows.
https://t.co/smWAeGaZAu
Irish Government : Move Gyms To Essential Services For The Mental & Physical Wellbeing Of The Irish People - Sign the Petition! https://t.co/NimF7MOlva via @Change