Godfried DOUGNON

Assistant Prof. at Brain Research Institute (Niigata University). Interests: #Autism, #ADHD, #Alzheimer's, #Parkinson's, #Mouse, #Zebrafish, #Cilia, #Aging

[Godfried DOUGNON @dgodfried1]

I'm happy to share my work on ube3a mutant zebrafish published in Molecular Psychiatry. A tiny fish shows environmental context-dependent social interaction!!!

https://t.co/oBBM1b4ARE

#Zebrafish #Autism #CellBiology #ZebrafishZunday #Neuroscience

[新潟大学脳研究所（公式） @niigata_nouken]

🔬研究成果🔎
脳病態解析分野のGodfried Dougnon助教、松井秀彰教授らの研究グループは、アルツハイマー病関連タンパク質APPが、損傷した細胞核から漏れ出すDNAや核タンパク質などの「核のごみ」を細胞外へ排出し、細胞を保護することを明らかにしました🧠

https://t.co/b1EQ42wPKa

[Godfried DOUGNON @dgodfried1]

I’m happy to share our latest paper!

A protective role for APP in nuclear waste clearance via lysosomal exocytosis | PNAS https://t.co/fbFLEFG0L7

[Godfried DOUGNON @dgodfried1]

Macrophage-mediated refinement of the dural lymphatic regulates social behavior: Neuron https://t.co/U1KtG8ripx

[日本神経科学学会 @jnsorg]

Announcement of the 2026 JNS-CNS Travel Award Program Awardees
https://t.co/92oiaKTj4M

[Godfried DOUGNON @dgodfried1]

Intestinal interoceptive dysfunction drives age-associated cognitive decline | Nature https://t.co/QSZuAsTEdj

[Godfried DOUGNON @dgodfried1]

Noninvasive tactile stimulation engaging a thalamic-amygdala circuit ameliorates mood dysfunction in mouse models of depression-like behavior: Neuron https://t.co/EQxUVSXhyO

[Godfried DOUGNON @dgodfried1]

Check out our latest article

A cost-effective method to assess light/dark preference and activity in zebrafish larvae: Heliyon https://t.co/3N6xetwNae

[Godfried DOUGNON @dgodfried1]

Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos | Nature Neuroscience https://t.co/B8NKUOv3OA

[Godfried DOUGNON @dgodfried1]

Neuronal networks in the dorsal hippocampus causally regulate rescue behavior in mice: Cell Reports https://t.co/pGLoV4ThGZ

[Godfried DOUGNON @dgodfried1]

Transfer to a naturalistic setting restructures fear responses in laboratory mice: Current Biology https://t.co/nH37C8pWY9

[Godfried DOUGNON @dgodfried1]

DNA-protein cross-links promote cGAS-STING–driven premature aging and embryonic lethality | Science https://t.co/gdrb6b6Jgc

[Godfried DOUGNON @dgodfried1]

RIN3 mutations impairing binding of the Alzheimer’s disease–associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology | Science Advances https://t.co/tfZrwhPJXa

[Godfried DOUGNON @dgodfried1]

Establishing the relationship between brain cellular senescence and brain structure: Cell https://t.co/6BjsFaDycu

[Godfried DOUGNON @dgodfried1]

Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2: Cell https://t.co/gkFp1Z5vWH

[Godfried DOUGNON @dgodfried1]

Angiopoietin-2 aggravates Alzheimer’s disease by promoting blood-brain barrier dysfunction and neuroinflammation: Cell Reports https://t.co/g3thRSDPTz

@CellReports

[Godfried DOUGNON @dgodfried1]

A mouse circadian proteome atlas:

@MolecularCell

https://t.co/dT2BFwbEiL

[Godfried DOUGNON @dgodfried1]

Spatial transcriptomics reveals effects of maternal immune activation and microbiome depletion on neurodevelopment

https://t.co/tpOPlN2m2g

@NatureNeuro

[Godfried DOUGNON @dgodfried1]

Infralimbic cortex neuromodulation attenuates anxiety and blocks fear ... https://t.co/iOl4vT4O0o

[Godfried DOUGNON @dgodfried1]

The age-pigment that quietly builds up inside long-lived cells has long been dismissed as a harmless by-product of aging. It may be more than we believe.

Check out my latest review on the topic in Translational Neurodegeneration:

https://t.co/WoQrJOHrbj

[Godfried DOUGNON @dgodfried1]

Anxiety can be an important component of autism. I am happy to share my paper using two zebrafish models (Translational Psychiatry)

Behavioral and molecular insights into anxiety in ube3a and fmr1 zebrafish models of autism spectrum disorders. https://t.co/vRyquW6a2b