Dirk Strauss

Software Developer, Coffee Drinker, Author and Professional Grouch. Views are my own.

[Ole Lehmann @itsolelehmann]

it's insane to me that this isn't all over mainstream media right now.

for the first time in human history, a drug built to reverse aging was just put into a living person

a company called Life Biosciences dosed the first patient in their trial for something called ER-100

it comes from a Harvard geneticist named David Sinclair

his theory is that aging comes from your cells losing track of how to read their own DNA

think of it like a computer. the hardware is fine, but the software slowly gets corrupted over the years, so the machine runs slower and slower until it stops

the instructions for a young, healthy cell are all still in there. your cells just lost access to them over time

so this drug does one thing: it reboots the cell back to the version of itself that knew how to run properly

they pull it off with three proteins that reset a cell to a younger state

and they proved it works before ever touching a human

first they restored vision in old mice. then they restored vision in monkeys with optic nerve damage, with no tumors and no signs of harm

so now they're testing it on people going blind from glaucoma and a nerve condition called NAION

they started with the eye on purpose. it's the cleanest place to test the idea, because they can inject it into one eye without it reaching the rest of the body, the cells there don't heal on their own so any improvement clearly came from the drug, and they can measure vision right down to the letters on a chart

the reset happens at the level of the cell, so in theory the same approach could one day rejuvenate the liver, the kidneys, even the brain

it won't be automatic though. every organ needs its own way of getting the drug into the right cells, plus its own round of safety testing. so it doesn't suddenly work everywhere the moment it works in the eye

but the eye answers the one question nobody could answer before: whether you can safely turn back the age of living cells inside a person

if the answer is yes, reaching the rest of the body comes down to delivery, one organ at a time. that part is hard, but it's the kind of hard you can engineer your way through

to be clear, this is an early safety trial. 18 people, 5 year follow up.

so nobody is gonna cure aging by next year

but if it works, we'll look back at this week as the moment the clock started running backwards for the first time

[Dirk Strauss @DirkStrauss]

@davidasinclair Definitely

[Apress @Apress]

Supercharge your .NET workflow with the latest #VS2022 tools! From #GitHubCopilot’s AI-assisted coding & testing to smarter debugging, line staging, and multi‑repo Git support—@DirkStrauss helps you build faster, cleaner & more confidently than ever.

🔗 https://t.co/73hIL0N0Ar

[Apress @Apress]

Supercharge your .NET workflow with the latest #VS2022 tools! From #GitHubCopilot’s AI-assisted coding & testing to smarter debugging, line staging, and multi‑repo Git support—@DirkStrauss helps you build faster, cleaner & more confidently than ever.

🔗 https://t.co/73hIL0N0Ar

[Dirk Strauss @DirkStrauss]

Visual Studio Shortcuts: The Full Guide to Coding Faster https://t.co/mmSPjbTp9m

[Dirk Strauss @DirkStrauss]

C# 14 New Features: A Developer Guide for .NET 10 https://t.co/LgIXPRhj8c

[Apress @Apress]

Supercharge your .NET workflow with the latest #VS2022 tools! From #GitHubCopilot’s AI-assisted coding & testing to smarter debugging, line staging, and multi‑repo Git support—@DirkStrauss helps you build faster, cleaner & more confidently than ever.

🔗 https://t.co/73hIL0N0Ar

[Stephanie Palazzolo @steph_palazzolo]

Trying to keep up after all this weekend's news? @erinkwoo does a great job of breaking it all down in this morning's AI Agenda:

https://t.co/RT8fCZVihP

[Dirk Strauss @DirkStrauss]

Rostr Pro is a school timetable and planning app built for students using cycle-day schedules.

Plan cycle days, track subjects, and stay ready for class. Upgrade to Rostr Pro to unlock homework, tests, and day planner tools.

https://t.co/C1eaC2XTGq

[Allie K. Miller @alliekmiller]

Anthropic is going nuts again on Cowork plugins 🔥

Financial services in particular - take notice of this list.

[Dirk Strauss @DirkStrauss]

@PrimeTimeNewsZA Click bait. The article says nothing about the video and the video itself shows nothing that can warrant the "horribly wrong" headline.

[Dirk Strauss @DirkStrauss]

Get the rundown on all .NET, VS Code, Azure & AI sessions at Build 2025 between May 19th till the 22nd, whether you’re in Seattle or online https://t.co/uSlAkgSkCZ

[Dirk Strauss @DirkStrauss]

Microsoft hires Mark D’Arcy (formerly Meta/Time Warner) to give Copilot a more engaging, relatable brand voice as it battles ChatGPT for AI assistant mindshare https://t.co/ozduj6SXSh

[Dirk Strauss @DirkStrauss]

Get the rundown on all .NET, VS Code, Azure & AI sessions at Build 2025 (May 19–22), whether you’re in Seattle or online https://t.co/uSlAkgSkCZ

[Dirk Strauss @DirkStrauss]

C# 14 preview introduces extension blocks for methods, properties & static members, making API extensions feel like native members https://t.co/ijQMs0WBPI

[Dirk Strauss @DirkStrauss]

azd v1.15.0 debuts new azd compose features, bug fixes & fresh project templates to speed up cloud-native dev workflows https://t.co/GKIqASfOxb

[9to5Mac @9to5mac]

Fortnite includes Apple IAP and Epic checkout, fate rests with App Store review https://t.co/f2VbHpvlnf by @apollozac

[Dirk Strauss @DirkStrauss]

Dev Proxy v0.27 Released

https://t.co/IQJMNMA5sF

[Dirk Strauss @DirkStrauss]

https://t.co/Eauq4VEX1A