DKFZ Epigenetics

The Division of Epigenetics at the German Cancer Research Center. Pursuing research on cancer epigenetics, epitranscriptomics, ...and marbled crayfish.

[DKFZ Epigenetics @dkfzEpigenetics]

@mrodpar When the cat‘s away, the mice will play 😉

[DKFZ Epigenetics @dkfzEpigenetics]

@SciWithRhi The CNS journals can accept and reject whatever they consider right for their profile. The problem is with the boards and panels that pay an inordinate amount of attention to these journals.

[Maizel Lab @maizel-lab.bsky.social @AlexisMaizel]

Game changing: @EMBOPress @Co_Biologists @eLife @PLOS @biorxivpreprint and others offer Review Commons: post preprint, preprints get peer-reviewed, then journal reach decision. This pooled submission accelerates publishing and reduces re-review. https://t.co/3vO1aWb1jp

[Nature Reviews Molecular Cell Biology @NatRevMCB]

@NatRevMCB proudly presents Focus on #Methylation in biology with 5 cutting-edge Reviews + commentary showcasing the latest understanding of the mechanisms and roles of methylation in animals and of its clinical relevance https://t.co/sr4KwvcrOb ALL Reviews are FREE for 1 month!

[Nature Reviews Molecular Cell Biology @NatRevMCB]

#Methylation Focus issue @NatRevMCB: Comment by Frank Lyko @dkfzEpigenetics on the importance of non-histone protein methylation in cancer therapy https://t.co/1RnEFVx9tT

[Center for Epigenomics, Einstein @EpgntxEinstein]

Please RT: come join our group and learn wet and dry bench techniques, equip yourself for an independent research career, collaborative project with @tuuliel #epigenetics

https://t.co/DncaEFGKIV

[CellNetworks @cellnetworks]

The programme is now online at https://t.co/7hersjTpfj ! From 3pm till midnight, you can take part in a number of exciting events offering insights into the range of international research taking place in and around HD and Mannheim.

[DKFZ Epigenetics @dkfzEpigenetics]

We are recruiting through the @dkfz postdoc program (https://t.co/ZYtWuK3Qux). If you are interested in a translational project on #skincancer and #SingleCell analysis, please contact us. Also see here for a more detailed project description:
https://t.co/19xmemR9Wy

[Eric Topol @EricTopol]

Challenging dogma, metastasis of #cancer occurs early: lineage of driver mutations via exome sequencing shows early seeding in > 80% of colon cancer patients
https://t.co/I5Fv3fCFp9
by @cncurtis @huzheng1 @StanfordMed and collaborators
@NatureGenet

[DKFZ @DKFZ]

Excellent #postdoc opportunities in basic and translational #CancerResearch. Apply now for a Postdoctoral #Fellowship
@DKFZ in #Heidelberg! Find out more at https://t.co/b7Cw2Pilnr. Application deadline: 15 September 2019. Please RT!

[Michael Boutros @Michael_Boutros]

How a Chinese Scientist Broke the Rules to Create the First Gene-Edited Babies via @WSJ #CRISPR https://t.co/1GGyvlqn96

[DKFZ Epigenetics @dkfzEpigenetics]

Our first single-cell paper is posted! Loss of fibroblast priming in aging human skin.

[bioRxiv Cell Biology @biorxiv_cellbio]

Single-cell transcriptomes of the aging human skin reveal loss of fibroblast priming https://t.co/NvS0WS5tod #biorxiv_cellbio

[Chris Mason @mason_lab]

The @NEBiolabs APOBEC-based enzymatic methylation protocol (EM-seq) is out! We see more even coverage across CpG islands & greater detection of CpG sites vs. WGBS; data coming soon from the @US_FDA @nygenome #SEQC2 #EpiQC study w/ @GenomeInABottle samples https://t.co/YvywCteqxj

[Molecular Cell @MolecularCell]

A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly https://t.co/4YxklZNE0V

[DKFZ Epigenetics @dkfzEpigenetics]

Epiproteomics, anyone? 😜

[Center for Epigenomics, Einstein @EpgntxEinstein]

I knew this day would come. Prepare to get your heads melted, #epigenetics researchers.

Transcription factors can be post-translationally modified.

These PTMs can affect their function.

Lysine methyltransferase inhibitors may affect TF PTMs.

Review:
https://t.co/p8yVNRI8te

[Gene Regulation @generegulation]

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries [Laura Wiehle @geejaytee Güenter Raddatz @chrsclrksn @dkfzEpigenetics @KarstenRippe Achim Breiling @TeifLab] https://t.co/86g9fKQmKF
5hmC loss > nuc gain > CTCF loss > 5mC spreading > gene↓

[The Scientist @TheScientistLLC]

“Nongenetic inheritance could, in fact, be genetic in origin.” https://t.co/D3OyUzifyh

[NatureEcoEvo @NatureEcoEvo]

Diversity of cytosine methylation across the fungal tree of life https://t.co/xb89bzkIM6

[Tschaharganeh Lab @tschaharganeh]

Scary article for those working with cell lines.

[DKFZ Epigenetics @dkfzEpigenetics]

Ecological plasticity facilitates farming of marbled crayfish in Madagascar. Check out our new paper: https://t.co/wcWnyHwPOl