dkylies

[Pablo J. Sáez / now posts in a better place (BSky) @pj_saez]

#ExSRRF, a new pipeline that allows to reach 25 nm resolution using widefield #microscopy
(useful for #cellbio, #ER_literature, clinics & more)

Tks for the invitation, @PuellesVictor, happy that @cellcommlab we could help you w this neat work

@NatureNano https://t.co/S4bQyNSePx

[dkylies @dkylies]

#ExSRRF

[dkylies @dkylies]

Super happy to present our new super-resolution pipeline that reaches 25nm in FFPE tissues using conventional widefield microscopes! Many thanks to our friends and collaborators!
https://t.co/tHe2sqPhX6
@PuellesVictor @Tobias_B_Huber @HCKH_Hamburg
@NatureNano

[Rafael Kramann, MD PhD @rkramann]

Great work from our Hamburg friends @PuellesVictor @Tobias_B_Huber 🔥🔥👇👇👇

[Costa Lab - @costalab.bsky.social @vanvanka123]

Amazing work from @PuellesVictor on nanoscale imaging on paraffin-embedded tissues!

[Nature Nanotechnology @NatureNano]

New content online: Imaging pathology goes nanoscale with a low-cost strategy https://t.co/oCmvDyOseM

[Nature Nanotechnology @NatureNano]

New content online: Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens https://t.co/6acredruFP

[UKE Hamburg @UKEHamburg]

Das @BMBF_Bund verlängert die Förderung des STOP-FSGS-Konsortiums unter Leitung des #UKEHamburg. Das Konsortium arbeitet u.a. an der Entwicklung neuer Diagnose- und Therapieansätze zur Behandlung der Nierenerkrankung #FSGS. @Tobias_B_Huber https://t.co/5uL0LqYnIE

[Tobias B. Huber @Tobias_B_Huber]

Hamburg news I: Topping out ceremony for our new research campus with Ulf Panzer from our department being the spokesperson of the Hamburg Center for Translational Immunology. @UKEHamburg @HCKH_Hamburg

[HCKH_Hamburg @HCKH_Hamburg]

What a great occasion to get this started! #KidneyWk
https://t.co/pXoeIifkcX - Hamburg Center for Kidney Health: From basic biology to disease mechanisms and patient care.
#Tobias_B_Huber

[dkylies @dkylies]

@HumphreysLab @Tobias_B_Huber @PuellesVictor Thank you so much for the kind Feedback!!

[Ben Humphreys @HumphreysLab]

Pretty astounding super high resolution wide field imaging of slit diaphragm & foot processes using ExSSRF & expansion microscopy, resolution of 25 nM, presented by Dominik Kylies, great work! @Tobias_B_Huber @PuellesVictor #KidneyWk

[Christoph Kuppe @KuppeChristoph]

Subcellular spatial proteomics of FFPE tissues🔥!
https://t.co/68z55o2uzA

[UKE Hamburg @UKEHamburg]

Forschende des #UKEHamburg haben neue Generkrankung identifiziert. International durchgeführte Arbeit zeigt: Gen Prolyl 3-Hydroxylase 2 (P3H2) stabilisiert Nierenfilter und Mutationen führen zu Nierenschädigung. Ergebnisse in @jclinicalinvest: https://t.co/QLprbYSZEt

[Urmila Anandh @AnandhUrmila]

Hyperkalemia leads to discontinuation of RAASi.
This unfortunately increase the risk of death.@ISNkidneycare meeting on managing DKD.@pecoitsfilho

[Katalin Susztak @KSusztak]

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy ⁦@jclinicalinvest⁩ by ⁦@Tobias_B_Huber⁩ and team https://t.co/3JJilCbzTH

[Brendon Neuen @brendonneuen]

Important new randomized trial in @JASN_News from @HeerspinkHiddo et al.

- SGLT2i + MRA lowers albuminuria more than either alone
- SGLT2i attenuates increases in K associated with MRAs

Demonstrating efficacy & safety advantages of combination treatment
https://t.co/WY0yELw8Vr

[JASN_News @JASN_News]

Kidney survival is poor in patients with circulating anti–GBM antibodies & severe kidney injury. This study found that single dose of imlifidase led to kidney survival without major safety issues in 10 of 15 patients with anti-GBM disease & poor prognosis https://t.co/6QSkm3p6AT

[Kenar Jhaveri @kdjhaveri]

Complement Activation and Thrombotic Microangiopathy Associated With Monoclonal Gammopathy: A National French Case Series https://t.co/prxVJfKHfd @AJKDonline

[JASN_News @JASN_News]

Data from the PEXIVAS trial challenged the role of PLEX in ANCA-associated vasculitides. This study found that PLEX was not linked with a better primary outcome in the whole study population, but identified a subset of patients who could benefit from PLEX https://t.co/gprd4xY4u6