Our aim is to study the role of DNA damage and mitochondrial function in Vascular, Immune and Neurological aging. A partnership between Brazil and Netherlands.
New publication from Menck's lab! ☀️
💡In XPV cells, high mutation burden stems from oxidative damage to NER proteins, not just TLS defects
💡Antioxidants could help protect XP-V patients from UVA-driven mutagenesis by boosting DNA repair
https://t.co/SnHB3Y9fYE
For all DNA repair and mutagenesis enthusiasts: the 7th edition of Fundamental Aspects of DNA Repair and Mutagenesis (VII FARM-DNA) is coming!🧬🛠
Registrations are open until July 31! To register and submit your abstract, visit: https://t.co/lTzgXAL4DW
See you there! 😉
For all DNA repair and mutagenesis enthusiasts: the 7th edition of Fundamental Aspects of DNA Repair and Mutagenesis (VII FARM-DNA) is coming!🧬🛠
Registrations are open until July 31! To register and submit your abstract, visit: https://t.co/lTzgXAL4DW
See you there! 😉
New publication from Menck's lab!!! 🧠
Analysis of transcriptome datasets specific to Cockayne Syndrome revealed significant changes in genes related to the MAPK, ERK1/2, PI3K-Akt pathways, neuronal processes and extracellular matrix metabolism.
https://t.co/mMNOUN4D0F
Vem aí a sétima edição do Fundamental Aspects of DNA Repair and Mutagenesis (VII FARM-DNA)! 🧬🛠️
O evento ocorrerá de 1-3/nov em São Paulo e contará com a participação de grandes pesquisadores da área, tanto do Brasil quanto do exterior.
Inscreva-se! https://t.co/lTzgXAL4DW
Check out the latest publication of Menck's lab! 🧬☀️
The study shows pyrimidine dimers are the primary lesions contributing to UVA-induced mutagenesis in human NER deficient cells and also that UVA induces mutational signatures similar to those of UVB!!!
https://t.co/IauFdvufyr
O programa Opinião de amanhã na @tvcultura estará imperdível, com a presença do Prof. Carlos Menck, que organizou o livro “A Evolução é Fato”, da @ABCiencias, e o grande @Pirulla25 🧬🦕 Não perca!!!
SAVE THE DATE!!! 📖🧬
No dia 19 de novembro, ocorrerá o lançamento do livro “A Evolução é Fato”, da Academia Brasileira de Ciências (@abciencias) e coordenado pelo Prof. Carlos Menck!!!
Inscreva-se gratuitamente e junte-se a nós para bater um papo sobre Evolução! 😉
Today we had our first in-person DNA moVIng meeting! 🤗
It was a great pleasure for us to receive Dr. @IngridPluijm and discuss what is being going on in our research projects! 🫀🧬
Excited to share our new publication in @repair_dna@Elsevier_Sci! We reveal the roles of Polɩ & Polκ in TMZ resistance in MGMT-deficient glioblastoma. Targeting these enzymes may boost TMZ's effectiveness.
Huge thanks to Dr. Menck & @WoodgateLab for their support!!
Our team is recruiting!
We are looking for an engineer to join us in our quest after the molecular mechanisms of replication stress response in human cells.
Position funded for 1 year, starting in Sept. 2024.
More info: https://t.co/7hwXxtva68
Chamando todos os graduanders das áreas biológicas e da saúde! Vem aí o XI Curso de Inverno do Laboratório de Reparo de DNA!!! 🧬🛠️
Mais informações em https://t.co/rhimT0QfO3
#genetica#biologiamolecular#reparodeDNA
No post do Dia das Mulheres e Meninas na Ciência, eu comentei que trabalhava com genes de reparo de DNA! Mas você sabe o que é reparo de DNA? 🧬
Vem que eu te explico neste fio! 🧵
Pretty new paper of my friend Fabiana León published in @Mut_Research! ☀️ Among the results, it shows that in C. crescentus, UVA and sunlight does not only activate photorepair, but also induce formation of lesions other than pyrimidine dimers. https://t.co/PL5AVh35hP
Exciting news! We have recently published a paper in #Photochemistry and #Photobiology! The work reveals a key role of pol iota as a backup for pol eta during translesion synthesis in NER-deficient XPC cells knocked down for either pol iota or pol eta 🧬
https://t.co/TavMThX4ap