Felix Marsh-Wakefield

Immunology PhD by day, musician by night.

[Orazio Vittorio @VittorioOrazio]

Excited to co-chair the 2024 Cancer & Immunology Ideas Forum with @DrHelenMcGuire, @doc_merlin and @sarah_sasson! Join us for groundbreaking discussions at the intersection of #Cancer Res & #immunology. @CancerSPHERE, @SydCancerPtnrs @UNSWMedicine @nanostringtech @BDBiosciences

[Givanna Putri @givanna90]

Very pleased to announce that our paper,
"SuperCellCyto: enabling efficient analysis of large scale cytometry datasets"
has just been published in Genome Biology!!

Paper: https://t.co/eCxO9284Yk
Code: https://t.co/1PlmXGKWmP

🧵👇

[Felix Marsh-Wakefield @doc_merlin]

Special thanks to @SydneyCytometry @CentenaryInst @Sydney_Uni @TomAsh_1 and all other authors

[Felix Marsh-Wakefield @doc_merlin]

Our preprint is out, using #IMC on #HCC tumours. We identified a unique neighbourhood within tumours consisting of VEGF+ perivascular macrophages and immune cells that could play a key role in angiogenesis and vascular permeability @angeferg @palendira C Santhakumar G McCaughan

[medRxiv @medrxivpreprint]

Spatial mapping of the hepatocellular carcinoma landscape identifies unique intratumoural perivascular-immune neighbourhoods https://t.co/ugWWj17T22 #medRxiv

[Belinda Phipson @BelindaPhipson]

The first paper from my lab, driven by an awesome postdoc @EV_wombat, and inspired by the 2022 @ozsinglecells/ASI hackathon!

[Cara Wogsland, PhD (she/her) @thinkCara]

CYTO shenanigans! @ISAC_CYTO #CYTO2023 #ISAC_CYTO

[Rafa Argüello @RafaJArguello]

What a team!

🤩 Great talks, discussions and fun at #CYTO2023 in @Montreal

So happy to finally meet in person with so many great colleagues @doc_merlin @TomAsh_1 @DrHelenMcGuire @Lauretalila Avrill Aspland 🤩 and many others.

🥰to see the @CIML_Immunology well represented

[Helen McGuire @DrHelenMcGuire]

📢 Epic battle of nature vs nurture!! 🔥Come along April 27th to *FREE Public Lecture* on all things immunology 🤩environmental influence! Check out amazing line up of experts 👇👇, hosted @Sydney_Uni with support from @ASImmunology
more info & rego https://t.co/28zHug5trz

[Felix Marsh-Wakefield @doc_merlin]

More work with Georges Grau and Linda Lin investigating #monocyte transmigration in #multiplesclerosis after #cladribine treatment https://t.co/RRYT6FDSU0 @IJMS_MDPI intermediate monocytes from cladribine-treated MS patients were impaired crossing a BBB @CentenaryInst @Sydney_Uni

[Felix Marsh-Wakefield @doc_merlin]

More great work from Florentina Aglas-Leitner and Georges Grau using #masscytometry in #multiplesclerosis after #alemtuzumab looking at #innatelymphoidcells in @ClinTransImmuno https://t.co/LLepAlMLP0 CD56bright #NKcells increased in MS and shifts between ILC1, ILC2 and CCR6+ILC

[Felix Marsh-Wakefield @doc_merlin]

Special thanks to Simon Hawke, Pierre Juillard, Annette Juillard @photoimmunology @SydneyCytometry

[Felix Marsh-Wakefield @doc_merlin]

Excited to share work with Florentina Aglas-Leitner and Georges Grau looking at #ILC in #multiplesclerosis patients with #cladribine in @SciReports. Cladribine depleted select subsets whilst immature ILC were higher https://t.co/4TCPFIDWOd @CentenaryInst @Sydney_Uni

[Felix Marsh-Wakefield @doc_merlin]

Proud of students work with Georges Grau @JCM_MDPI #multiplesclerosis issue. Rachel Ford & Kristy Nguyen found CD4+ TEM & CD8+ TCM had impaired transmigration across BBB in two MS cohorts after #cladribine https://t.co/SzRzxQ6h36 or #alemtuzumab https://t.co/cdRPJKWJJw

[Felix Marsh-Wakefield @doc_merlin]

@LinaDanl @DrNayanB @Claudiocounoupa @TricckyLab @Fenglab_usyd @jclinicalinvest Congrats!

[Felix Marsh-Wakefield @doc_merlin]

A fairy tale paper with @Dr_KaziNahar looking forward to what comes next!

[Mainthan Palendira @palendira]

Out now @JCI_insight our work on immunotherapy-induced colitis. A great collaborative work with @MelanomaAus @amenzies9 @ProfGLongMIA @ProfRScolyerMIA @inespiresilva @JWilmott38 study led by @Dr_KaziNahar and supported by @doc_merlin https://t.co/TD2LNC186T

[Thomas Ashhurst @TomAsh_1]

This week we ran our first @ASImmunology systems immunology hackathon to tackle emerging challenges in #singlecell #multiomics & #cytometry analysis, supported by @ChanZuckerberg @GriffithUniVC & @ozsinglecells. Astounded by what this group achieved in just 2 days - stay tuned!

[Felix Marsh-Wakefield @doc_merlin]

Thanks for the help team! @TomAsh_1 @dianashinko @Givanna90 @mnread @DrHelenMcGuire @photoimmunology @SydneyCytometry 👨‍💻👨‍🔬🔬⚗️

[ICB - the journal @ImmunolCellBiol]

B cells play a major role in #MultipleSclerosis, with many successful therapies removing them from circulation. Featured this month, @doc_merlin et al @Sydney_Uni @CentenaryInst find peripheral B cell dysregulation associated with MS relapse. #ICBnews
https://t.co/3BwK9PLuvq

[Mainthan Palendira @palendira]

We have started some exciting work with Prof Geoff McCaughan on Human Hepatocellular Carcinoma. As a prelude the team has looked at the available approaches to spatially resolving these tumours in this review article. Great work @doc_merlin @angeferg https://t.co/G1UWy035e5

[Thomas Ashhurst @TomAsh_1]

Immensely proud to see @Givanna90's novel time-series #singlecell #cytometry clustering tool '#TrackSOM' online with Cytometry A. This was a wonderful multidisciplinary collaboration across @Sydney_Uni including @mnread @nickjck @doc_merlin and others.

https://t.co/D7ZpwfCzLy

[Felix Marsh-Wakefield @doc_merlin]

Merry Xmas! This is a picture of liver by IMC. Don't ask what markers they are, I picked them because they're pretty #imaging #masscytometry #pretty #Christmas @SydneyCytometry @angeferg @palendira