Nick

liker of brains 🧠 , birds 🦜, and being outside 🏔️

[Nick @docdocrace]

We are recruiting another brain injury doc at UC Davis in Sacramento, CA!

Exciting stuff

Please reach out if interested to learn more. Come join us in NorCal 🤙

More info here: https://t.co/WqEhQiEbPn

[Blessen C. Eapen, MD @BCEapenMD]

CMS Officially Recognizes Brain Injury as a Chronic Condition #braininjury #tbi https://t.co/hC6TYh3b7W

[Brain Injury Research Center (BIRC) of Mount Sinai @SinaiTBI]

[1/2]
On #InternationalWomensDay, we celebrate women's achievements in science, medicine, & research!

We also take this time to acknowledge that many #TBI studies are primarily comprised of men, leaving gaps in our understanding of sex & gender differences in TBI...

[Veera Rajagopal  @doctorveera]

A mind-blowing paper has come out today in @Nature

In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (https://t.co/Rk8oZJ0bUj).

Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome.

The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution.

Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell.

When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part.

The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival.

The conclusion of the paper is metaphorically a quote from the Jurassic Park movie:

“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (https://t.co/UlxRlb86CT)

https://t.co/zA9OAqSoAu

[Nick @docdocrace]

@DanDaneshvar Kudos to you and the whole team for this fantastic work. Glad this hypothesis is gaining traction in larger studies! Count me among the believers in cumulative energy, symptoms or not

[Dan Daneshvar, MD, PhD @DanDaneshvar]

In the largest study of CTE to date:
concussion does not cause CTE

The predicted total force to the head that athletes experienced over their lifetime was the best predictor of who had CTE, and how severe it was

[Kathryn Hyzak, PhD @DrKateHyzak]

Staggering statistics on the incidence of traumatic brain injury due to intimate partner violence in Canada @CanadaSoar

[Brain Injury Research Center (BIRC) of Mount Sinai @SinaiTBI]

Many studies on #TBI have primarily focused on men, leaving LARGE GAPS in the understanding of sex or gender differences of TBI.

The BIRC is committed to conducting studies with a diverse range of participants to close the gender gap in TBI research
#BrainInjuryAwarenessMonth

[Julie Stamm, PhD, ATC @JulieStammPhD]

This is NOT a blood test for concussions!

It may be useful for determining if a patient needs a CT scan because they are at higher risk of having a brain bleed.

It does NOT show whether or not someone has a concussion!

#braininjuryawarenessmonth

https://t.co/1Lk84hjiuG

[Kathryn Hyzak, PhD @DrKateHyzak]

Happy #BrainInjury (BI) Awareness Month! This fact sheet helps ⬆️awareness of BI in the U.S. Two points I’ll highlight:

1️⃣We don’t have accurate prevalence estimates of BI b/c not everyone seeks tx, or BI is improperly identified

2️⃣Overdoses=BI! Substance tx providers take note

[Nick @docdocrace]

@gbosslet burning bay leaves can be useful for banishing rituals 👹. true story

also 🔥 addition to tomato-based eggs in purgatory or poached cod

[Nick @docdocrace]

@av0gadra another one of their greatest hits is making people in pain go get a med every single day. medicine has comedy figured out

[Nick @docdocrace]

#SCIIncubate is wonderful - a fantastic program/experience! @NeuroVigor Therapeutics benefited tremendously from the program last year

Highly recommend for anyone trying to commercialize technology geared toward helping individuals living with #SCI

Application details below👇

[Praxis Spinal Cord Institute @praxis_sci]

Applications for Praxis SCI Incubate 2023 are open! Do you have an early prototype #SpinalCordInjury innovation that could impact quality of life for those living with #SCI? Praxis #SCIIncubate program can help expand your reach.
Deadline to apply Nov 20: https://t.co/2eWS3l6g9L

[Anne Ricketts @Global_BIA]

23 July is Global Brain Injury Awareness day! Please help us bring understanding & necessary public by sharing our posters. Press release - https://t.co/g1PuspQbCg
Help - https://t.co/9x1WrxVhjH
Learn - https://t.co/Lk4JgbageW
#Globalpicnic

[Nick @docdocrace]

PPAF press release here:

https://t.co/QwiYVevz09

[Nick @docdocrace]

Some colleagues/friends are organizing a donation to PPAF (matched 1:1 through June 30) to support reproductive/abortion rights. Funds are not earmarked.

If so inclined, we welcome your support. Funds go directly to PPAF from this GoFundMe

https://t.co/3DVqQTMlS2

[Nick @docdocrace]

@dino_comics Bird?

[Neuro Vigor Therapeutics @NeuroVigor]

Neuro Vigor is seeking preclinical and clinical collaborators interested in studying the impact of reactive aldehyde species (RAS) in various disease states.

Learn more from our website:
https://t.co/cGetl1mUnT

[Andrew McCoy, MD @AMcCoy_MD]

Excited for this work to get published! 😊 So proud of my dept and co-residents @UPMC_PMR for their commitment. So fun working with Austin Davis and huge thanks to @HoutrowMDPhDMPH for her mentorship.

#ADA #Accesstocare @AAPhysiatrists
https://t.co/bDFD4d6YOt

[Nick @docdocrace]

@AMcCoy_MD @UPMC_PMR @HoutrowMDPhDMPH @AAPhysiatrists congrats, y'all! (or should I say yinz)