I am thrilled to share that our story on Intramolecular Bivalent Glues has now been published in @Nature. This has been an incredible team effort alongside my co-leads Matthias Hinterndorfer and Angus Cowan, with the support and guidance from @georg_e_winter and @alessiociulli.
📢#SEQT_articles
Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution and its application for the inhibition of MDM2/p53 interaction as a proof-of-concept
Authors: @dr_illo@SpringGroupChem
🔗https://t.co/YdUM6IrHuG
🚨 We are hiring a Chemist for the @AlessioCiulli/@Boehringer team at CeTPD.
Join our dynamic drug discovery team and help us find effective PROTACs for oncology targets.
Find out if you'd be right for this position and apply at https://t.co/XzLm41MEHd
#ChemJobs
We have enjoyed a wonderful day celebrating 20 years of the Spring Group! 🥂 Big thank you to all of the speakers, alumni and current members for a day filled with science and fond memories! 🧪
📢#MedChemJobs
Contrato Postdoctoral - 17 meses
Descubrimiento de nuevos antimaláricos
Síntesis química en el grupo del Dr. Diego Muñoz-Torrero y estudios biológicos en el grupo del Dr. Xavier Fernández-Busquets del IBEC/ISGlobal.
📆Febrero 2023
🔗https://t.co/aqfewjF58C
Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI-001 in in vitro Models of Prostate Cancer Drug Resistance (Asim, Spring) @RaduNicolescu4; @SpringGroupChem; @dr_illo#openaccess https://t.co/T49a3QCOP6
Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI-001 in in vitro Models of Prostate Cancer Drug Resistance (Asim, Spring) @RaduNicolescu4; @SpringGroupChem; @dr_illo#openaccess https://t.co/T49a3QCOP6
We're delighted to share our most recent work in antibody conjugation, featuring all-in-one disulfide bridging using TetraDVP reagents. Now in @ChemicalScience, check it out! https://t.co/3TSxum0Zlx
@ChemCambridge
Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis https://t.co/cGmCE4MRr2 #mdpipharmaceuticals a través de @MDPIOpenAccess
David Spring at @ChemCambridge, Jason Carroll at @CRUK_CI and colleagues use divinylpyrimidine reagents for the synthesis of antibody–drug conjugates.
@springgroupchem
https://t.co/qZCtgfsWaV
@dlozanme @masc2021 Well done @dlozanme !! Remember to thank the committee for the invitation for a flash “chromatography”, definitely your distinguishing mark 😝
🚶
🌔
ALL OVER THE MOON! 🤩
Our paper for the synthesis of Mechanically Planar Chiral Rotaxanes is out online in @NatureChemistry#chemtwitter#chemistry
https://t.co/cwf5Kzkhrs