Jeroen den Dunnen

Principal Investigator at the Amsterdam UMC. Studying antibody-dependent inflammation during infection, arthritis, and (long) covid.

[Jeroen den Dunnen @DrDenDunnen]

Our paper is (finally) out in @CellRepMed: antibodies from #LongCOVID patients transfer symptoms to mice, pointing to a potential causal role for autoimmunity: https://t.co/K3za9wNsH2 @amsterdamumc @UMCUtrecht 1/12

[Jeroen den Dunnen @DrDenDunnen]

Looking to build your own research line and work towards a tenured position @amsterdamumc?

Join CIMM as tenure-track Assistant Professor in infectious diseases, immunology, or microbiology.

Apply by 23 September:
https://t.co/4X9klkczrl

#TenureTrack #AcademicJobs

[@longcovidtheanswers @longcovidanswer]

Could Autoantibodies Help Explain #LongCOVID?

At #ISLCPAIS, @DrDenDunnen shares early research suggesting autoantibodies from some people with Long COVID can affect muscle, nerve, heart and blood-vessel cells in laboratory models.

#LongCOVIDtheanswers #PAIS #Autoimmunity

[Jon Douglas @atranscendedman]

University of Namur researchers studied 13 long COVID patients and found their IgG antibodies bound sensory neurons and caused temporary pain sensitivity in mice, supporting autoimmune pain as one piece of long COVID.

https://t.co/nYcr70MUrC

[Jeroen den Dunnen @DrDenDunnen]

@epkedj @CellRepMed @amsterdamumc @UMCUtrecht Jazeker, we gaan dit binnenkort ook bij ME doen. En daarna voor post-Lyme en post-Q koorts.

[Jeroen den Dunnen @DrDenDunnen]

Our paper is (finally) out in @CellRepMed: antibodies from #LongCOVID patients transfer symptoms to mice, pointing to a potential causal role for autoimmunity: https://t.co/K3za9wNsH2 @amsterdamumc @UMCUtrecht 1/12

[Jeroen den Dunnen @DrDenDunnen]

@DuaneStorey Good suggestion, nice control experiment.

[Jeroen den Dunnen @DrDenDunnen]

Big thanks to our funders @StLongCOVID and @ZonMw for making this research possible! Hats off to the team: @oliverch77, Brent Appelman, @HLDMWillemen, the incredible @Eijkelkamp_N, and all others. And a special thanks to all involved patients! 12/12

[Jeroen den Dunnen @DrDenDunnen]

Big picture:

We establish a patient-to-mouse model of Long COVID driven by antibodies.

This gives us a way to:
🔬 study mechanisms
💊 test treatments 11/12

[Jeroen den Dunnen @DrDenDunnen]

I had almost forgotten about this #MECFS interview, but it still holds true 🙂: https://t.co/DUt9i9H3lo

[Jeroen den Dunnen @DrDenDunnen]

For the first time, a prestigious Dutch #VICI grant (€ 1.5M) has been awarded to research on post-acute infection syndromes (#PAIS). I’m deeply grateful for this opportunity to further indentify the underlying mechanisms: https://t.co/93qKwxGMQQ

[Stichting Long COVID @StLongCOVID]

📷 We starten vandaag met iets bijzonders: de Community Challenge voor biomedisch onderzoek naar #LongCOVID: https://t.co/I23fOioDh8