Dr Jack Kreindler

Physician, researcher, explorer. Founder & CEO @CuriaHealth @ CHHP. Hon Research Fellow @Imperialcollege

[Dan Go @CoachDanGo]

This is your brain on sleep deprivation.

Scientists in Canada launched the largest study on how lack of sleep affects the brain.

They created games that tested skills like reasoning, language comprehension & decision making.

They had one participant repeat these tests in an MRI machine.

Here's what they found:

On the left is a normal night of sleep.

On the right is when it's deprived of 4 hours of sleep.

The colored areas are the activity happening in your brain. Notice the lack of activity on the right side.

Researchers found there was less activity in the frontal & parietal lobes, which are crucial for decision making, problem solving & mood control.

You are simply not at your best when you don't get enough sleep.

Another study done at the University of Oslo found that lack of sleep leads to reduced clearance of substances from the brain.

These substances are many of the same waste products that are seen to accumulate in the brains of Alzheimer's patients.

Some recent studies suggest that poor sleep contributes to higher levels of beta-amyloid protein in the brain, which lead to the amyloid plaques found in the Alzheimer's brain.

If you want a healthy brain avoid long term sleep deprivation.

What should you do?

• When deprived of sleep avoid making big decisions & pause before reacting to an emotion.

• Fix your sleeping habits. If you can't get enough hours, focus on increasing your sleep quality to make up for it.

Sleep is the best legal performance enhancing drug on the planet.

Make it a priority now so you can protect your brain for later.

[Dr Jack Kreindler @drjackUK]

@drjasonfung @DoctorTro It’s all part of being on a Cashogenic Diet. Maintaining a Cashogenic state can lead to profound paradoxical biases, and, in extreme cases, hypocritical crises. But in general it just lowers your integrity sensitivity and enhances bank balances.

[Dr Jack Kreindler @drjackUK]

Great having @LaraLewington in the lab pushing the boundaries of human fitness amazingly. Living example of slowing the pace of ageing. https://t.co/6HQGvfe8Jm

[Lara Lewington @LaraLewington]

As the person no-one at school wanted on their sports team (big sigh when they got me, the left over one), I'm pretty chuffed that filming my @ITV Healthy Ageing show today, this happened.... (and thank you @drjackUK!).

[Dr Jack Kreindler @drjackUK]

@balderton @Mosaic_VC 🙏

[Dr Jack Kreindler @drjackUK]

I could not be more proud see our WellFounded Health service be publically launched by another truly committed advocate for Founders’ health & performance! 👏
https://t.co/hnKbNyKIp9
@balderton @Mosaic_VC

[Balderton Capital @balderton]

We are pleased to be launching our Founder Wellbeing and Performance Platform, based on research among 230 founders as well as 20 years of experience investing in Europe’s best entrepreneurs.

Read more👇
https://t.co/eObDpJ5qKt

[Dr Jack Kreindler @drjackUK]

@LaraLewington @ITV All your hard work paid off over the years. You have the fitness of an elite endurance athlete!!

[Dr Jack Kreindler @drjackUK]

@Dlloydlevine @protolifemedia @dr_ran_crooke @WellFounded_

[David Levine @Dlloydlevine]

My article on flavanols as promoting cognitive health.
Are You Getting Enough Flavanols? @protolifemedia https://t.co/BxjJtZW44Y

[Dr Jack Kreindler @drjackUK]

@biogerontology @LongevityTech Important to educate everyone here. It is indeed a rebrand but at a time where inflection points are happening fast.

[Dr Jack Kreindler @drjackUK]

Thanks to my colleage De Ran Crooke for spotting this. Important study. Doesn’t sit so well with my belly personally but working on ways round that. Any ideas @dr_ran_crooke ?

[Dr Ran Crooke @dr_ran_crooke]

“In this comprehensive dose-response meta-analysis, a total of 181 studies with 220 treatment arms, containing 14,505 participants were included. Soluble fiber supplementation improved serum TG, TC, LDL cholesterol, and Apo-B concentrations” https://t.co/7G2NruDNGY

[Dr Ran Crooke @dr_ran_crooke]

“In this comprehensive dose-response meta-analysis, a total of 181 studies with 220 treatment arms, containing 14,505 participants were included. Soluble fiber supplementation improved serum TG, TC, LDL cholesterol, and Apo-B concentrations” https://t.co/7G2NruDNGY

[Dr Jack Kreindler @drjackUK]

@FFHealthTech @LaraLewington @BBCClick Looking forward to introducing you @LaraLewington

[Founders Forum HealthTech @FFHealthTech]

🎤 Speaker announcement ���

We're ecstatic to welcome @LaraLewington, Presenter, @BBCClick as a Leaders Stage HealthTech speaker at #LTW2023 😎

[Dr Jack Kreindler @drjackUK]

don't know about you but that's better than I've thought about it. I wonder what it feels like, now I know the answer? For some reason all I feel now is the need for a cheeseburger.

[Dr Jack Kreindler @drjackUK]

I don't suppose this is the first time Chat GPT has been asked to answer the ultimate question of life the universe and everything. Still, it feels oddly comforting that the answer remains precisely the same as Deep Thought's response those many millions of years ago.

[Dr Jack Kreindler @drjackUK]

5/5 and ultimately...