โWhen you hear hoofbeats, think horses, not zebras.โ This relates to an ego-driven cognitive bias called overcalling zebras.
In medical practice , ego may lead you to consider a rare, exotic diagnosis too early, without sufficient evidence.
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I'm a cardiologist. I have spent twenty years watching cholesterol destroy arteries, trigger heart attacks, and kill people I care about.
Today, Eli Lilly presented data that may begin to end that era.
VERVE-102. A single infusion. One dose. It uses base editing to permanently turn off the PCSK9 gene in your liver.
Presented today at the European Atherosclerosis Society Congress:
88% reduction in PCSK9.
62% reduction in LDL cholesterol.
Sustained up to 18 months.
No treatment-related serious adverse events.
One infusion. Not daily pills you forget to take. Not monthly injections. One dose โ and your cholesterol may stay low for the rest of your life.