Abdulsamet Erden

researcher in #lupus #neonatal lupus #fmf #rheumatology

[Alberto Giraldo @alb_giraldo]

A recent study identified increased vein wall thickness (VWT) as a novel #vascular feature in systemic #lupus erythematosus (SLE), which may indicate subclinical venous involvement, regardless of antiphospholipid antibody or antiphospholipid syndrome status:
◦ VWT was notably increased in SLE patients compared to healthy controls and rheumatoid arthritis patients, emphasizing the unique vascular involvement in SLE.
◦ Portal vein wall thickness was independently associated with #thrombosis, suggesting its potential as a vascular risk marker.
◦⭡P-selectin, growth differentiation factor 15, and citrullinated histone 3 correlated with venous changes, highlighting biochemical markers of thrombo-inflammatory processes.

*Yildirim D, Erden A, Ibrahimkhanli N et al. A new characteristıc of systemic lupus erythematosus: subclinical vein involvement—an in-depth biochemical and imaging study. Rheumatology (Oxford), 2025.
🔗https://t.co/6n8vFV6mhF

[Abdulsamet Erden @drsameterden]

This raises an important question: should #APS be considered in the differential diagnosis for all patients presenting with #moyamoya-like findings? Is this speculation valid and supported by the evidence?

[Abdulsamet Erden @drsameterden]

Alternatively, we aimed to explore whether the radiological findings resembling #moyamoya observed in #APS patients could represent ischaemic and haemorrhagic lesions caused by APS rather than true moyamoya syndrome.

[Abdulsamet Erden @drsameterden]

Alternatively, we aimed to explore whether the radiological findings resembling #moyamoya observed in #APS patients could represent ischaemic and haemorrhagic lesions caused by APS rather than true moyamoya syndrome.

[Abdulsamet Erden @drsameterden]

One of the critical objectives of our study was to determine whether the association between #moyamoya syndrome and conditions like #APS is coincidental or if, as suggested by the diagnostic criteria, these patients should indeed be classified as having moyamoya #syndrome.

[Abdulsamet Erden @drsameterden]

One of the critical objectives of our study was to determine whether the association between #moyamoya syndrome and conditions like #APS is coincidental or if, as suggested by the diagnostic criteria, these patients should indeed be classified as having moyamoya #syndrome.

[Abdulsamet Erden @drsameterden]

Intersecting Pathways: #Moyamoya Syndrome and #Antiphospholipid #Antibodies—A Comprehensive #Review of Clinical Insights, Therapeutic Considerations and Prospective Perspectives - Vasi - 2025 - Acta Neurologica Scandinavica - Wiley Online Library https://t.co/9iiVIo6xHn

[Abdulsamet Erden @drsameterden]

Intersecting Pathways: #Moyamoya Syndrome and #Antiphospholipid #Antibodies—A Comprehensive #Review of Clinical Insights, Therapeutic Considerations and Prospective Perspectives - Vasi - 2025 - Acta Neurologica Scandinavica - Wiley Online Library https://t.co/9iiVIo6xHn

[Abdulsamet Erden @drsameterden]

🚨 New pub alert!
#Myosteatosis was more prevalent and strongly associated with clinical features, including #lung disease and #esophageal dilatation, than #myopenia, underscoring the importance of #muscle #quality.

https://t.co/NTAyWdf4gr

@Ertugrul_cagri @rizacankardas

[Abdulsamet Erden @drsameterden]

#COVID-19 or #SLE / #LUPUS: Attention to similarity. #Arthralgia and #myalgia may signal a #rheumatic disorder. Clinicians should consider both #infectious and non-infectious conditions resembling COVID-19, especially during the #pandemic https://t.co/OInJPE9hIT via @Shareaholic

[Abdulsamet Erden @drsameterden]

#CXCL-13 correlate with #SLEDAI scores, anti-#dsDNA antibodies, and #C3/C4 levels. Thus, CXCL-13 may serve as a promising diagnostic biomarker for #NPSLE’s challenging diagnosis and management. #SLE #LUPUS

[Abdulsamet Erden @drsameterden]

🚨 New pub alert!
#CXCL-13 levels are significantly higher in #NPSLE patients—especially in active cases—than in those without #neuropsychiatric involvement and healthy controls. #SLE #LUPUS
https://t.co/t7gIz3V9Qt

[Abdulsamet Erden @drsameterden]

@iamddlado We did not apply the criteria with CAPS patients.

[Abdulsamet Erden @drsameterden]

Our latest work has been published in the International Journal of #Rheumatic Diseases #IJRD. Assessment and comparison of the 2023 ACR/EULAR #APS criteria with the revised #Sapporo criteria. #antiphospholipid syndrome #systemic #lupus #erythematosus #SLE
https://t.co/iJvSZ1H66q

[Abdulsamet Erden @drsameterden]

🚨 New pub alert!
#Vascular #Calcification in #Takayasu #Arteritis; Relationship with #Metabolic Syndrome, Left #Ventricular Mass Index and #Intima-Media #Thickness.
Our newest paper published @HjCardiology led by @rizacankardas @4fc021c64f83427.
https://t.co/Hx3iyIKNEx

[Abdulsamet Erden @drsameterden]

🚨 New pub alert!
#Calcineurin inhibitors experience in unplanned #pregnancies with active #lupus disease: A retrospective observational study

https://t.co/pwz2FwrBnY

@rizacankardas @4fc021c64f83427

[Abdulsamet Erden @drsameterden]

Serum levels of #HMGB1, a nonhistone nuclear protein that has an important role in #psoriasis, are significantly higher in #patients with #psoriatic #arthritis than in patients with #psoriasis and healthy controls. @fsgbmm
https://t.co/mMjT29dR4N

[Abdulsamet Erden @drsameterden]

Our study (#Colchicine-intolerant familial Mediterranean fever patients: A comparative study between different colchicine doses and #IL-1 inhibitor monotherapy) is published in the International Immunopharmacology. #FMF #anakinra #canakinumab https://t.co/6uSQqKRI12

[Abdulsamet Erden @drsameterden]

#SLE is the most commonly associated disease with #APS, being present in approximately 35% of cases. Since the majority of the patient group in our study had #APS that was secondary to #SLE, non-criteria antibody positivity may be linked to the #immunological activity of #SLE.

[Abdulsamet Erden @drsameterden]

I am delighted to share my most recent ''Non-criteria #autoantibodies in #antiphospholipid #syndrome may be associated with underlying #disease #activity'' publication in the Ir J Med Sci.
https://t.co/4F22pGNgx9 @billtormey @armaganberkan @ozlemm_karakas @OmmaDr @MDbaharozdemir

[Abdulsamet Erden @drsameterden]

I am delighted to share my most recent ''Non-criteria #autoantibodies in #antiphospholipid #syndrome may be associated with underlying #disease #activity'' publication in the Ir J Med Sci.
https://t.co/4F22pGNgx9 @billtormey @armaganberkan @ozlemm_karakas @OmmaDr @MDbaharozdemir

[Seminars in Arthritis and Rheumatism @seminarthrheum]

Accepted for publication:

Demonstration of diffuse venulitis on MRV might help with diagnosis of Behcet's Disease in this case-control study.

https://t.co/chIGhQ6HfR

[Dr. John Cush @RheumNow]

Paradoxical Rxns (PR) & biologics in TReasure database: 2867 RA & 5316 SpA pts; 5-yr FUV found 136 pts (1.7%) developed the PRs; 60% w/ 1st biologic, after median 12 mos, 93% psoriais (pustular 60%, palmoplantar 31%), many better w/ another TNFi https://t.co/5tybXZZVKW

[Abdulsamet Erden @drsameterden]

Happy to share our editorial:
''The outcome of COVID‐19 in patients with autoimmune rheumatic diseases: Comparable to the general population or worse?'' @EzgiDenizBatu1 https://t.co/aE4Dv3oV4W