This #SKResearch in @FrontMedicine explores how Cyclosporine, an immunosuppressant, impacts our immune system & endothelial cells, which help control what passes through our bloodstream.
Read ➡️ https://t.co/xSt9ZKj0pQ
Grateful to all who made my MSc thesis work possible!
In our in-vitro model of blood outgrowth #endothelialcells, cyclosporine led to:
⬇️ #glycocalyx
⬇️ CFH binding & cofactor activity
⬆️ C3 & C5b9 deposition
⬆️ endothelial cell injury
@UofTIMS@uoftmedicine@SickKidsNews
Intra-dialytic hypotension (IDH) is the most common serious adverse event in paediatric haemodialysis. Read this Original Article on implementing a PedHDfluid program using the Model for Improvement methodology aimed at decreasing IDH.
https://t.co/qalfzRl9EH