🚀 We are introducing PerturbPair (with @TakaKud0) — a platform that combines parallel Perturb-seq and optical pooled screening (OPS/PerturbView) in primary cells to systematically map at massive scale how genetic perturbations reshape cellular states across modalities.
With wonderful collaborators @TakaKud0, @AnaMeireles, @AntRios, @jchuetter, @MinOta, @ORozenblattRosen, @LeviAGarraway, @KGeiger, @avtarsingh, @jkpritch, and Aviv Regev.
Paper link: https://t.co/fnSUymW95s
Happy to share a new preprint! Ebola virus condensates don’t just contain viral RNA🧬 — they also capture and regulate host mRNAs , reshaping interferon responses and viral adaptation.
#Virology#RNA#Condensates
https://t.co/FEgR2m9WSp🧵👇
Announcing a huge v2.1 release for Bento, enabling even more scalable analysis of spatial transcriptomic data! 🏃💨
Plus, our paper is now published at @GenomeBiology after a roller coaster of preprints, submissions, revisions, new authors, and datasets 🎈 @NoorsherAhmed 1/6
I am excited to finally share Bento, our toolkit for subcellular analysis of spatial transcriptomics data! @NoorsherAhmed https://t.co/aV0HXdjtGo (1/8)