Dylan Duchen

Genetic Epidemiology + Computational Immunology Postdoc with @skleinstein , @Yale-@Boehringer Fellow | Previously: Genetic Epidemiology @JohnsHopkinsSPH

[airr_community @airr_community]

🚀 Registration is now OPEN for AIRR Community Meeting VIII: Decoding and Recoding Immunity! Join us June 8–11, 2026 at Yale University (USA) or attend virtually. 💸 Early-bird rates available until April 15! 🔗 Register: https://t.co/xJniCj1abW

[Michael Baym @baym]

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

[bioRxiv Bioinfo @biorxiv_bioinfo]

Gfa2bin enables graph-based GWAS by converting genome graphs to pan-genomic genotypes https://t.co/umrWEuvEDN #biorxiv_bioinfo

[Genevieve Wojcik, PhD MHS @genandgenes]

Heading to #ASHG24 and looking for a postdoc position?

Interested in genetic epidemiology, specifically gene x environment in diverse pediatric cohorts?

I'll be here all week so find me to talk about opportunities with myself and @priya4genes at @jhugeneticepi in Baltimore!

[Dylan Duchen @DylDuch]

@ZhiYu_ACGT @MGHMedicine @harvardmed Congratulations! Fantastic news

[Kenneth Hoehn @hoehnousk]

New paper with @skleinstein and @28Cole on how to build B cell lineage trees with paired heavy and light chain BCRs with Dowser! Paired H+L improved accuracy, but *most* methods highly biased when mixing #SingleCell and bulk #BCR (1/3). https://t.co/m7a54fyAcv

[Priya Duggal @priya4genes]

Exciting work by Laura Chen and @RebeccaMMunday on Astrovirus and host genetic susceptibility in a region with lots of diarrheal infections. So much to learn about the interaction of pathogens and hosts. @DylDuch @genandgenes @PKorpe @OFIDJournal
https://t.co/xTubrUVh4Z

[bioRxiv Bioinfo @biorxiv_bioinfo]

nf-core/airrflow: an adaptive immune receptor repertoire analysis workflow employing the Immcantation framework https://t.co/cCEzJdIsno #biorxiv_bioinfo

[fanofactor @fanofactor]

Interested in high-throughput B cell receptor repertoire analysis? Register for the "2024 Immcantation Users Group Meeting" on Jan 25, 2024 10-2PM (ET). Program and FREE registration at: https://t.co/Gb6wnkzdgi #immcantation #AIRRseq #RepSeq #Bcell #meeting

[Dylan Duchen @DylDuch]

Excited to be presenting at #ASHG2023! Characterizing the immunoglobulin locus is hard, especially with short reads - stop by PB3313 @ 3pm 11/2 to hear about our approach using a sequence variation graph and whether it might be useful in your own work!

[Priya Duggal @priya4genes]

Excited to share this viewpoint in @jidjournal.
Titles are hard, but this one seemed to fit well!🎼🎼🎼

https://t.co/J3MjR2JKOU

[Nicholas Wu @wchnicholas]

Our new study systematically analyzed the effect of immunoglobulin V (IGV) gene allelic polymorphisms on antibody binding using >1000 publicly available antibody-antigen complex structures. We also experimentally validated some interesting findings. https://t.co/ZyQHTejHyu (1/12)

[Dylan Duchen @DylDuch]

Deadline to apply for a great interdisciplinary + hybrid industry/academic postdoc fellowship (I might be biased) is 4/18, any potential applicants - please reach out if you have any questions! https://t.co/DMxBou3Qsk

[Dylan Duchen @DylDuch]

@mschotsaert Why not fungi?

https://t.co/hLgqrfrw0Z

[Erik Garrison @erikgarrison]

Building pangenome graphs (many-way whole genome alignments) without technical bias seems hard. Most methods use heuristics to simplify construction. We show that with a few weird tricks, we can easily avoid bias and easily build graphs of very large sizes https://t.co/f9AcQWu28Q

[Dylan Duchen @DylDuch]

@CoreyAferiat @roosterdouglas

[Dylan Duchen @DylDuch]

@CoreyAferiat

[Erik Garrison @erikgarrison]

Safely sharing non-identifiable sequences from private cohorts of complete genome assemblies: https://t.co/UjRZCtPaMI (Or: How to build a global pangenome from siloed data)

[Dylan Duchen @DylDuch]

@CoreyAferiat

[Johns Hopkins COVID Long Study @covidlongstudy]

"When I wish upon a star.."

Despite all our efforts to wish this away, COVID is still here. And we need to learn more.
If you
* have had COVID (recently or not so recently)
* NOT had COVID
* 18 or older, living in the US

Please participate and share.

https://t.co/SQB5UTaj3B