We found a robust feature of cancer cell plasticity in bulk tumors using TmS, a mixed-genome-adjusted transcriptome deconvolution metric. This feature has demonstrated molecular and clinical relevance across cancers (brief summary below). Our preprint: https://t.co/VH5zIBseQQ.
Celebrate International Day of Women and Girls in Science by taking a few minutes to read about these amazing women and consider the ways you can support the #WomenInScience you know!
My group developed a predictive model for calling de novo mutations in patients with inherited cancer syndromes, and found a higher rate of de novo TP53 mutation carriers than previously described. On bioRxiv: https://t.co/H9LtikU7Ta. Thanks for data! @SharonSavageMD@judygarber5
Shin et al develop cancer-specific penetrance estimates for #LiFraumeni Syndrome (LFS) with the goal to better inform patients & improve risk management of healthy individuals from LFS families. @meganf1@sharonsavagemd@WenyiWang4@MDAndersonNews https://t.co/VJ8cdOh9gQ 1/2