In a collaborative study, Group Leaders Judith Zaugg (EMBL) and Moritz Mall (DKFZ) identified a liver protein, called PROX1, that preserves cell identity and halts cancer formation in preclinical mouse models paving the way for new liver cancer therapies.
https://t.co/pUOjQEhwH0
#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. https://t.co/ddl4mJGvhA #CancerBiology
Researchers from the @DepBiomedicine , the @embl and the @DKFZ have uncovered a key mechanism regulating cell fate plasticity. In their groundbreaking study, @AryanKamal_ from the @zauggj group together with @ecyrblim from the @MoritzMall group identified safeguard repressors, such as PROX1, that maintain cell identity and prevent liver cancer. 👇👇https://t.co/1PDwXFIwoX
@NatureGenet #CellFate #Plasticity #CancerResearch #LiverRegeneration #GeneRegulation #PROX1 #Hepatocytes #Cholangiocarcinoma #TumorSuppression #Transdifferentiation
Excited to share our first preprint with @zauggj@embl! We screened 1,296 transcription factors for repressors that block unwanted plasticity and found many putative tumour suppressors. PROX1 stands out as hepatocyte safeguard that prevents #livercancer. https://t.co/qayayMO6xd
Alright, let's take a closer look at some of these pencil tests from Akira! Look at this amazing tracking shot! That tunnel! I bet a lot of folks assume this was 3D CGI but NOPE. It was hand drawn!
#Akira#Akira30#アキラ#PencilTest#2DAnimation#Sakuga
Time-lapse movies of Mars as seen before & during the current global dust storm. (Images captured by NASA's Mars Reconnaissance Orbiter.)
https://t.co/T3XgDuJZ7W