Eduardo Flores

An irrational scientist trying to figure it out. Whatever "it" really is. All tweets are my own.

[Tim Ferriss @tferriss]

Just saw YOU CAN SEE EVERYTHING by @A24 and it blew my mind. I'll probably watch again this week. The number of WTF moments is staggering (e.g., “Whoa, a cock in a shower! ... Holy shit, why is an infant just standing on a table behind them? ... Abbott and Costello?!”

It also inspired the fuck out of me. Editing that film almost certainly took 10 years off of the lives of @nathanfielder, @lanceopp, and team. If they’d gone 80%, it would have been terrible. Instead, they went 100%, and it’s a masterpiece. I've seen all sorts of buzz online around their "marketing playbook," but here's their marketing secret: make the product so ridiculously good and unique that people can't stop talking about it.

"Where am I 3/4-assing?" is the question haunting me this week. What a gift.

[Patrick Hsu @pdhsu]

Cmd Shift A in Google Chrome - you're welcome

[herculez gomez @herculezg]

Messi & Inter Miami are getting worked by PSG. Worked.

Excuse me. I meant Real Madrid.

[Danfeng Cai @DanfengCai]

So happy our paper on TFE3 fusion oncoprotein condensates in translocation RCC is online at Cell Reports! Great collaboration from @EnedaToska, @VitoRebecca1, Marston Linehan and @jihk99 labs. Proud of the work of our trainees Choon, Jane, Bujamin et al https://t.co/q4l69x79rw

[Josh Riback @SuperSciJew]

In lab's #FIRSTPREPRINT, we present methods to measure nanometer organization around & between specific proteins in condensates. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.

[Eduardo Flores @eflores500]

@bioplymrsinvivo ah ok, just FYI, Feb 14th is a Friday, thanks for the timely response!

[Eduardo Flores @eflores500]

@Grapes_nMyMouth likewise broseph! 🐺

[Ben Steiner @BenSteiner00]

I’ve seen a lot of the Toronto running community, but this guy wins.

[Eduardo Flores @eflores500]

**Shout** 😅

[Eduardo Flores @eflores500]

📢 Excited to share our research with @shaharsu & @mvstaller on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions regulate transcription in unique ways. https://t.co/VWFX1MOYA0
🧵 Highlights:

[Eduardo Flores @eflores500]

Shut out and thank you to Max Staller (@maxvstaller) for sharing his insights, discussions, and providing the activity data for all our correlations. Deep gratitude as well to Aleah R. Camacho, @estefaniacuevaz , and @MaryBMcCoy1 for their contributions throughout the project!

[Shahar Sukenik @shaharsu]

New work from @eflores500 examines the relationship between disordered ensemble structure and activity in transcription. Read more here 👇

[Jeff Lotthammer @jefflotthammer]

Glad to see this out. It was a lot of fun working with Ryan to scale up Metapredict to enable accurate proteome level predictions of disorder in seconds. We leveraged our throughput to systematically interrogate the prevalence of disorder across the tree of life!

[jackie pelham @PelhamJackie]

We are happy to announce that Rhythmidia, a modern tool for analyzing circadian phenotypes in race tube assays, is out in @PLOSCompBiol.

Led by the talented @atkeeley00!!
https://t.co/fQBYQhAo6r (fig1) 🧵1/6