The EMBO Journal

Rapid publication of research in molecular, cell & organismal biology.
Part of @EMBOPress. Tweets by editors.
On Mastodon: @[email protected]

[The EMBO Journal @embojournal]

Like @EMBO, we will be sharing publications of future articles and new @embojournal issues mostly on an alternative platform - tune in if you would like to stay informed!

[The EMBO Journal @embojournal]

here's where you'll find us:
https://t.co/uVCtqxW3dj

[The EMBO Journal @embojournal]

Like @EMBO, we will be sharing publications of future articles and new @embojournal issues mostly on an alternative platform - tune in if you would like to stay informed!

[The EMBO Journal @embojournal]

SIRF: Sergio Acebron @acebron and colleagues develop a new biosensor reporting on functional interactions between dsDNA sensor STING and IRF3, allowing to capture STING activation upon various triggers
https://t.co/K0V907M0eL

[The EMBO Journal @embojournal]

Synergistic & antagonistic activities of IRF8 & FOS enhancer pairs during an immune-cell fate switch
Graf, Nikolaou et al show individual enhancers act as stage-dependent, dynamic safeguards during CEBPA-induced B-cell-to-macrophage transdifferentiation
https://t.co/qMe0Vu2gGi

[The EMBO Journal @embojournal]

Immediate early splicing (IES): Florian Heyd and colleagues show that phosphorylation-controlled gene expression changes upon T-cell activation also includes a rapid and transient splicing switch that controls de novo translation
https://t.co/VXjfpXXazJ

[The EMBO Journal @embojournal]

Cryo_EM shows how barley NLR immunoreceptor MLA13 binds a fungal RNase-like effector from pathogenic grass powdery mildew
Aaron Lawson, Paul Schulze-Lefert et al @ceplas.bsky.social
https://t.co/KsGPPcMKll

[The EMBO Journal @embojournal]

Greatwall kinase is key for mitotic entry in metazoans, so how can worms do without it?
Pintard et al find sole canonical MAST kinase, KIN-4, assumes its role in PP2A-B55 phosphatase inhibition & coordination of cell divisions & development in C. elegans
https://t.co/vs6VtzVYS1

[The EMBO Journal @embojournal]

Somatostatin released by pancreatic δ-cells triggers local cAMP and Ca2+ signaling in primary cilia of nearby β-cells, to modulate their function beyond acute suppression of hormone release
Olof Idevall-Hagren and coworkers
https://t.co/YNFNPjLsXz

[The EMBO Journal @embojournal]

Local weakening of cell-extracellular matrix adhesion triggers basal epithelial tissue folding
Andrea Valencia-Exp��sito, María Martín-Bermudo et al
https://t.co/hmQtcKqff3

[The EMBO Journal @embojournal]

In issue 4:
FAM134B isoforms control ER dynamics in myogenesis
Bacterial virulence factor targets both neutrophils & complement system
Special pericytes in pulmonary capillaries
Cover: 1st plant spliceosome structure by Yichen Lu, Ke Liang & Xiechao Zhan
https://t.co/a5HDeLoicb

[EMBO @EMBO]

EMBO is on Bluesky, and we look forward to meeting you there!

https://t.co/mRozC2yUur

[The EMBO Journal @embojournal]

Hansong Ma and coworkers identify POLDIP2 as a novel mitochondrial exonuclease interacting with CLPX protease and promoting elimination of paternal mtDNA during Drosophila spermatogenesis
https://t.co/WbxQOJTQVm

[The EMBO Journal @embojournal]

Identification of Poldip2 as exonuclease essential for paternal mtDNA elimination allows assessing the importance of this process for ensuring proper spermatogenesis and sperm functionality in Drosophila
Hong Xu and colleagues
https://t.co/13EJU54LzC

[MPIPZ Cologne @mpipz_cologne]

📢Paper Alert! 👏👏New publication out @embojournal by the group of Paul Schulze-Lefert @mpipz_cologne and colleagues at UoC and @Westlake_Uni on immune receptor engineering for plant resistance.👉https://t.co/uQe2XtqPRh
#Engineering #plants #Immunology
https://t.co/Zkrftx0snn

[Pancreatic Cell News @PancreaticCell]

Under the leadership of Dr. Olof Idevall-Hagren, scientists show that #IsletCell primary cilia endow #somatostatin with the ability to regulate islet cell function beyond acute suppression of hormone release. 🧪

@embojournal | https://t.co/ZDwhvILsaW

[The EMBO Journal @embojournal]

Modulation of tumor inflammatory signaling and drug sensitivity by CMTM4
https://t.co/VRH9Sb1gw0

[EMBO Reports @emboreports]

Congratulations to @JuliaVorhauser @mansfeldlab @ICR_London for winning the @EMBOReports poster award at #EMBOmetabolicDiseases !

[The EMBO Journal @embojournal]

Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals adaptive strategies for alleviating the consequences of aneuploidy in cancer – including increased expression of DNA replication and repair factors
@ZStorchova and coworkers
https://t.co/BuWpiGS0bJ

[The EMBO Journal @embojournal]

CDK4/6 inhibitors transiently induce a senescence-like state in breast cancer cells, which however cannot be eliminated by senolytics - but Boshi Wang and colleagues @Demarialab1 find that they are instead sensitive to lysosomotropic agents!
@UMCG_ERIBA
https://t.co/j9MXGZk2fZ

[The EMBO Journal @embojournal]

Yeast proteotoxic stress response: Intrinsically disordered Roq1 reprograms specificity of ubiquitin ligase Ubr1 towards four distinct classes of substrates using its N-terminal arginine linked to a short hydrophobic motif
Sebastian Schuck and colleagues
https://t.co/4Sbggy6OSl