Excited to share this new collaborative @EmboMolMed work from my lab @ChildrensAL & @jdowling007 labs. Work highlights efforts to generate a new animal model for X-linked myopathy with excessive autophagy (XMEA) and perform corrective drug screening. 1/n https://t.co/hRgrJQLfId
🧬 Dr. Abdel-Majid Khatib's team at @BRIC_Bordeaux explored the therapeutic potential of targeting proapelin cleavage sites in metastatic #CRC by introducing apelin-dm, a variant resulting from alteration in proapelin cleavage sites.
@EmboMolMed | https://t.co/zZtszwFjtq
Repression of #apelin Furin cleavage sites provides antimetastatic strategy in #ColorectalCancer
By B. Demoures, G. Siegfried, AM Khatib & colleagues @Inserm
➡️https://t.co/gaoExYs1DR
Portimine A #toxin causes #SkinInflammation through ZAKα-dependent #NLRP1 inflammasome activation
By P. Brehmer, F. Roca, F. Zhong, J. Common, E. Meunier, P. Hess & colleagues
🗞️https://t.co/axB3TLUCcD
➡️Read this review by A. Bleckmann & colleagues that provides a comparison of in vivo, ex vivo, and in vitro models for studying #tumor - #microbiome interactions in early-onset #ColorectalCancer
🗞️https://t.co/q4JUmUjZKT
📢New issue online!
The cover highlights the study by M Breßer, K D Siemens, R Schneider et al. on the role of reactive resident #macrophages in surgery-induced #GutInflammation & resulting enteric #neurodegeneration.
Image by R. Schneider & colleagues
📰https://t.co/PQlhA15fFK
Are you attending the #EMBOmetabolicDiseases meeting in beautiful Torremolinos? So is our editor Deniz Senyilmaz Tiebe! Talk to her if you are looking for a home for your paper or about scientific publishing. @EMBOevents@EMBOPress
Online today ➡️#MicrobialMetabolites tune #amygdala neuronal hyperexcitability and #anxiety -linked behaviors.
By W. Yu, Y. Xiao, S. Pettersson, H.S. Je & colleagues @dukenus
🗞️https://t.co/jErmbcyPSh
An AI-assisted morphoproteomic approach is a supportive tool in #esophagitis -related #PrecisionMedicine
By S. Mattern, S. Singer & colleagues at Tübingen University
➡️https://t.co/mZSZ4riZv0
📢Review by K. Nadeau & colleagues at Harvard T. H. Chan School of Public Health 👉 #Exposomics: a review of methodologies, applications, & future directions in #MolecularMedicine
https://t.co/TwYd4LnTI5
Review by M. Moll & D. Baumjohann @UniklinikBonn
➡️Boosting human immunology: harnessing the potential of immune organoids.
🗞️https://t.co/AXIDfhdkXP
"Improving the odds of survival: transgenerational effects of infections"
👉Read the review by V. Spanou, T. Andriopoulou, E. Giamarellos-Bourboulis & M. Neteai at University of Athens & @radboudumc
🗞️https://t.co/5RfxDutcFS