Excited to finally see this work come out online @NaturePortfolio. In this work we identify FOXO1 overexpression as a strategy to improve CAR T cell persistence and metabolic function using CAR T derived from mice, healthy donors and cancer patients.
https://t.co/Osl4bTw6Md
Excited to share the latest work from the lab led by @ImranHouse and @emsderrick. Using CRISPR HDR we report a method to generate bona fide reporters for a secreted factor of interest, in our case CXCL9. https://t.co/J6BQK1nEt1