Pharmacology for EHS

EMSP 3004 Pharmacology I for EHS in the Emergency Health Sciences Degree Program at UT Health San Antonio.

[Pharmacology for EHS @emsp3004]

Ondansetron is a serotonin receptor antagonist; drugs in this class are the most effective drugs available for suppressing nausea and vomiting associated with anticancer drugs.

[Pharmacology for EHS @emsp3004]

I will be correctly the scores on Quiz 8.

[Pharmacology for EHS @emsp3004]

Reminder that Quiz 10 is this weekend and is a little different than previous ones.

[Pharmacology for EHS @emsp3004]

This week reviews anticancer medications and meds for the GI tract.

[Pharmacology for EHS @emsp3004]

Anticancer drugs:

[Pharmacology for EHS @emsp3004]

Exam 4 is open for this weekend.

[Pharmacology for EHS @emsp3004]

True Story Part 2: COX-1 inhibitors reduce platelet aggregation...good sometimes but not before major surgery.

[Pharmacology for EHS @emsp3004]

True Story Part 1: Co-worker's mom was scheduled for surgery but was cancelled the day of bc she said she was taking ibuprofen during the week. Why?

[Pharmacology for EHS @emsp3004]

After an inflammatory insult (injury, infection etc.), arachidonic acid is released. The COX enzyme works on arachidonic acid that causes the release of several prostaglandins

[Pharmacology for EHS @emsp3004]

Congenital adrenal hyperplasia (CAH) results from an inborn deficiency of the enzymes needed for glucocorticoid synthesis. The condition is marked by increased production of ACTH, because the pituitary attempts to enhance glucocorticoid synthesis.

[Pharmacology for EHS @emsp3004]

Menopausal hormone therapy (HT), formerly known as hormone replacement therapy (HRT), has three approved indications: suppression of vasomotor symptoms, prevention of urogenital atrophy, and prevention of bone loss and osteoporosis.

[Pharmacology for EHS @emsp3004]

Sitagliptin (Januvia) inhibits an enzyme named dipeptidyl peptidase-4 (DPP-4) that breaks down incretin hormones. As a result, levels of GLP-1 and GIP incretin hormones are increased allowing more insulin production.

[Pharmacology for EHS @emsp3004]

Agents that stimulate insulin release include:
— Sulfonylureas: first and second generations
— Meglitinides: repaglinide (Prandin) and nateglinide (Starlix)

[Pharmacology for EHS @emsp3004]

Quiz 7- 15 multiple choice questions on hypothalamic, pituitary, and adrenal cortex medications- due Sun Oct 20.

[Pharmacology for EHS @emsp3004]

Drugs for acromegaly are generally reserved for patients who do not respond to other therapies or for whom these therapies are not viable options.

[Pharmacology for EHS @emsp3004]

Propylthiouracil (PTU) is an anti-thyroid drug. It is used for the most common hyperthyroidism condition - Graves' disease.

[Pharmacology for EHS @emsp3004]

The Glycosylated hemoglobin level, HbA1c, tells you your average level of blood sugar over the past 2 to 3 months. For people without diabetes, the normal range for the hemoglobin A1c level is between 4% and 5.6%.

[Pharmacology for EHS @emsp3004]

AVANDIA (rosiglitazone maleate) is an oral antidiabetic agent which acts primarily by increasing insulin sensitivity. AVANDIA is used in the management of type 2 diabetes mellitus.