#ENDpoiNTs_EU strives to develop a testing battery of human relevance to screen the impact of endocrine disruption on neurodevelopment. Funding from @EU_H2020.
Estrogens & androgens shape hippocampal growth & function, linked to spatial cognition. This review explores the evidence for EDC-induced learning & memory disruption: https://t.co/cBXvlaZbno
#Hormones#BrainDevelopment#EDCs#CognitiveAbilities
High oxidative stress linked to inflammation in BPA study. Low doses increased proinflammatory cytokines & damaged liver tissue, showing a non-monotonic dose-response. Perinatal exposure caused liver damage & inflammation in offspring. More information: https://t.co/UayhlIixgy
🔬 A Xenopus laevis model allowed functional recovery assessment after demyelination and remyelination. A correlation between histological remyelination and clinical performance was found. Learn more: https://t.co/W4htaEUAQ2
#MultipleSclerosis#Remyelination#XenopusLaevis
🧠Advancements in neurotoxicity testing! 3D BrainSphere models based on human induced pluripotent stem cells allow thorough neural characterization. Spike sorting distinguishes various neuronal subtypes. Read more: https://t.co/T9Sw8rOITy
#neuroscience#neurotoxicity
🐀 Exciting new research! A method to quantify 23 steroid hormones from adult and neonatal rat liver & plasma was established using enzymatic treatment, SPE & LC-MS/MS. Read more: https://t.co/AgoVJHgSSQ
#LCMS#EDCs#steroidhormones
🧠 Take a look at your brain!
🔬 These images capture neural progenitor cells' journey to human #neurons. Adherence protocols provide targeted cell cultures for our focused research.
📢Associations between real-life exposure levels of phthalates and altered play behaviors in children were found in a recent publication https://t.co/Wd65rB3IxM #EDCs#GenderDevelopment
A state-of-the-art review on the effects of #EndocrineDisruptingChemicals calls for more restrictive use to prevent human exposure during sensitive phases such as brain development
@JoelleRuegg
https://t.co/PQAVbwF6HM
Exciting new research from our partners in Paris, reveals that embryonic exposure to a mixture of EDCs found in human amniotic fluid can significantly alter gene expression of neurodevelopmental genes and decrease tadpole motility. Read the study here: https://t.co/cHOfsssgdZ
Recent research from our partners in Paris @BDemeneix@umr7221 highlights that even short-term developmental exposure to low levels of bisphenol F can adversely affect neurogliogenesis and olfactory behavior in adult mice https://t.co/XUbMeCNUx3
A new study from our @UmeaUniversity partners presents an in silico approach for a first-tier identification of compounds with potential endocrine activity in Receptor-mediated molecular initiating events https://t.co/I26GxOt5b6
A new study from our @humantechnopole partners presents an approach for in vivo/ in vitro alignment of neurodevelopmentally relevant processes by benchmarking transcriptomic profiles of brain organoid against fetal corticogenesis. Read more here: https://t.co/qCgWNpCvYg
The next EURION Cluster Annual Meeting is held in Amsterdam on 30-31 Jan 2023 🥳
On 30 Jan there is an online session open to any stakeholders. In this session, the cluster projects highlight their key achievements so far.
#EDCs#H2020@HorizonEU#EURION
https://t.co/BW5bhBiEXJ
The ENDpoiNTs coordinator, Prof. @JoelleRuegg we will presenting in the upcoming symposium on Endocrine disrupting chemicals and Human Health. Last day of registrations! For information see:
https://t.co/7XS5BQIXCS
🚨New @ERGO_EU publication alert🚨
An atlas of #thyroid#hormone receptors’ target genes🔍🧬
A unique compilation of sequencing data focusing on thyroid hormone T3, its receptors, modes of action, targets & roles, an easy-to-use & convenient tool!
👀👉https://t.co/xrobOc8kPa