e payne

[Palestine Daily News✌️🇵🇸✌️ @Palestinedaily1]

This is Israel, world

Israel did this

Repost please

[e payne @epayne963928]

It's hard to imagine that a large pharmaceutical company would not by be interested in the technology owned by Curis. My only concern is whether the company will survive long enough to negotiate a sale. IMO $CRIS

[e payne @epayne963928]

@LongTimeHistory ?

[e payne @epayne963928]

$CRIS Chat GPT how often does EMA approve a drug before FDA? "2022 study published in JAMA Network Open found that from 2011 to 2020, the EMA approved 85 (43%) of 197 new drugs before the FDA." Maybe we hear from EMA before FDA?

[e payne @epayne963928]

$CRIS I recommend going to Curis's website and looking at the updated corporate presentation - I am unable to post a link: Corporate Presentation

[e payne @epayne963928]

$CRIS current Curis orphan drug designations: Emavusertib 12/3/2024 PCNSL & 4/2021 AML and MDS, Fimepinostat 2015 large DLBCL

[e payne @epayne963928]

$CRIS Part 2: compare recent cancer drug approvals with Curis's Emavusertib: Take Aim trial RR AML 21 patients 10 of 19 evaluable with ORR = 52.6%, 6 CR =31.6%

[e payne @epayne963928]

$CRIS Part 1: ChatGPT what cancer drugs with orphan status were FDA approved in 2024 ? ORR and CR rates: 1, Bizengri 64 eval. ORR 33% CR 1.6%, 2. Tecelra 44 eval. ORR 43.2% CR 4.5%, 3. Vorasidenib PFS of 27.7months vs 11.1 w/Placebo ORR and CR ?, 4. Amtagvi ORR 36% CR3%

[e payne @epayne963928]

$CRIS Will Curis's time come?: Eli Lilly to buy cancer drug developer Scorpion Therapeutics for up to $2.5 billion

[e payne @epayne963928]

https://t.co/I3Gddaw8lw now add patent protection to the mix. With only 8.5M shares outstanding, CRIS stock price has the potential to increase exponentially, IMO $CRIS

[e payne @epayne963928]

@sububoston Patent does mention IRAK 4 inhibitor is part of Patent. Am I reading this wrong?

[e payne @epayne963928]

How is it that a company with a patented cancer treatment using IRAK 4 is only worth $35 MILLION? Anxiously awaiting EMA or FDA orphan drug approval of Emavusertib $CRIS

[e payne @epayne963928]

https://t.co/uwDshmU9ys $CRIS

[e payne @epayne963928]

Abstract: The present disclosure relates to methods of treating certain diseases and disorders (e.g., cancer) with a combination of an IRAK4 inhibitor, a BCL-2 inhibitor, and a nucleoside analog.
Type: Grant
Filed: February 25, 2022
Date of Patent: December 31, 2024
$CRIS

[Just Jack @7Veritas4]

NOAA has been tracking the formation of Hurricane Milton for days.

They sent hurricane hunters to determine its speed and intensity.

They've identified its path across Florida.

Their data will save hundreds if not thousands of lives.

NOAA is one of the many departments that would be broken up and downsized in a Trump regime.

[e payne @epayne963928]

$CRIS 8 new recruiting sites PCNSL, now 37 at https://t.co/IfiK9uROa1: Record History | ver. 19-20: 2024-07-11 | NCT03328078 | https://t.co/K621IoGc6k

[e payne @epayne963928]

New clinical trial update to PCNSL study. 8 additional sites now recruiting. Now 37 if I counted correctly. Not sure if the link will post. If not go to https://t.co/IfiK9uSlZz Record History | ver. 19-20: 2024-07-11 | NCT03328078 | https://t.co/K621IoGJVS

[e payne @epayne963928]

60% ORR in this r/r with 3 CR's and one unconfirmed CR. What is the FDA waiting for? There are no available treatments and life expectancy of these patients is about 2 months. Hopefully either the FDA or the EMA (European FDA equivalent) will act soon. $CRIS

[Blue Checkmark @AreWeThereYet03]

@epayne963928 $CRIS 60% ORR. 3 CRs one unconfirmed CR and 2 PRs.

CRu and a PR both still on drug. 4/10 or 5/10 CR rate is likely.

[e payne @epayne963928]

Anyone have the results on the additional pcnsl patients? $CRIS