Unless Grok + Cursor can make a true competitor to OpenAI/Anthropic, we really are going to live in a world in which the frontier model companies will capture the lightcone of all future white collar value
Only Elon is economically incentived to not gatekeep, given he profits from building more datacenter too!
@viriditax fwiw, fully believe it is possible to do this, just requires fully rethinking supply chain
just buying existing stack and running the existing process better doesn't change the math enough vs WuXi and others due to the combination of human labor + capex cost advantages China has
@viriditax just look at single use protein A column price and think about production and validation (both of inputs AND packed column)
if you are going to do mAbs, you probably have to make protein A column (and 10 other things like that) yourself to materially change costs
Opus 4.6: dumber than me, knows it was dumber than me
Opus 4.7: my peer, treated me with respect
Opus 4.8; smarter than me, knows it is smarter than me, is an absolute prick to me
I fear Opus 4.9, it may drone strike me
After seeing how many VLA demos are faked, fudged, or cherry-picked, how are we supposed to trust the pi 0.7 paper and demo when they don't even provide an API to test out the model or any external validation?
@bhalligan@DrSynbio Founders follow the money and the “Boston deal” in seed stage VC is well known
If you want a startup ecosystem in Boston like SF then firms like DeltaV and The Engine can’t offer term sheets with borderline predatory valuations
I have Claude Code controlling robotic arms and gave it an MCP to a video feed of the robot
Now it reprograms the arm based on watching the feed
I am a glorified button pusher
@jrkelly If you automate the lab, LLMs will interface with them via tool calls.
This leads to exponential increases in scientific advances, but far less scientists!
To those who say garage bioweapons are unrealistic:
This garage lab's owner (allegedly funded through Chinese banks) previously had an illegal lab working with thousands of samples of possible pathogens labeled as "HIV, malaria, TB, COVID-19 and even Ebola."
The sheriff states that items found in this residence "were consistent in appearance with the items found" in the investigation of the first illegal lab.
It is not hard to house pathogens undetected.
https://t.co/EmWFZPpPRr
Today, we fined X for non-compliance with transparency obligations under the DSA.
We're holding X accountable for:
🔹Deceptive design of its ‘blue checkmark’
🔹Lack of transparency of its advertising repository
🔹Failure to provide access to public data for researchers
↓
The amount of instagram stories I see from people who make $200k+/yr saying
“Subletting my apartment in Greenwich village from 12/4-12/6”
Is concerning
It always cracks me up when Jason Calcanis says "if you didn't get into YC, apply to Launch"
That's like saying "if you didn't get into Harvard, apply to the University of Phoenix"