Eva-Maria Strauch

Associate Professor, Washington University

[Eva-Maria Strauch @Estrauch3]

Congrats to Raulia for her paper published today! I am very excited about our work: ConforPSSP and ConforFold, a combined framework for conformational sampling. Also, comparing state-of-the-art methods using deep learning. https://t.co/FE3SnlDzCx

[Eva-Maria Strauch @Estrauch3]

Check out our most recent preprint with a pipeline to gain more insights into confrontational sampling: https://t.co/s8jDRFPLFE

[Eva-Maria Strauch @Estrauch3]

Congratulations David! Well deserved. It has been an honor to be part of this journey.

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Eva-Maria Strauch @Estrauch3]

@NobelPrize Congratulations David! Well deserved. It has been an honor to be part of the journey.

[Eva-Maria Strauch @Estrauch3]

Great job Karen! Our systematic disulfide stabilization paper is out, featuring better RSV immunogens.

[Eva-Maria Strauch @Estrauch3]

Firefly petunia in my kitchen! So fun to see

[Institute for Protein Design @UWproteindesign]

We're advancing a new global agreement signed by 100+ leading scientists to ensure AI technologies for protein design are developed responsibly. This field can deliver medicines, vaccines, and other innovations that benefit all.

https://t.co/pTlFtBWHNh

https://t.co/XYn986dEAt

[Eva-Maria Strauch @Estrauch3]

@Louchene_Charaf Thanks!

[Eva-Maria Strauch @Estrauch3]

I am a bit, but our work on establishing a general method to stabilize the prefusion conformation of class I viral fusion proteins got published https://t.co/G2zZe6XeNo!

[Eva-Maria Strauch @Estrauch3]

Excellent work by my (then) graduate student (now postdoc) @KJ__Gonzalez !!

[WashU Medicine Division of Infectious Diseases @WashUMedID]

Please join us to meet new investigators, Eva-Maria Strauch @Estrauch3 and Chen Shen @Chen_Shen_01 on Nov. 2 at 1 pm, EPNEC, Rm 301!
https://t.co/8qoWCWgATp

[Eva-Maria Strauch @Estrauch3]

I assume a 5 percentile for an NIAID R01 grant should get funded?! If so, I am looking for postdocs! It's a happy day.

[Eva-Maria Strauch @Estrauch3]

@AnastassiaVoro2 Congrats!!!

[Walter Isaacson @WalterIsaacson]

Great article. The next REALLY big thing will be using AI and LLMs to generate thousands of new proteins, including new hormones and enzymes and antibodies. @geochurch @demishassabis
@_RobToews via @forbes https://t.co/jTOPrpaOKp

[Joseph Watson @_JosephWatson]

It's so great to see our RFdiffusion paper now live @Nature. This article from @ewencallaway gives a great overview of RFdiffusion and protein diffusion models more broadly, and also highlights some of the ways people are already using it in their own research!

[Eva-Maria Strauch @Estrauch3]

I am happy to announce, we will be moving to WashU at the end of this month where we will join the Infectious Disease Division! #WashUMed

[CIDER_UGA @CIDER_UGA]

CIDER is looking forward to seeing you in just 2 weeks! @CEIRRNetwork #ASV2023

[Eva-Maria Strauch @Estrauch3]

Our work has been constantly inspired by the pioneers in the field. Such as @McLellan_Lab , Peter Kwong, @BarneyGrahamMD.

[Eva-Maria Strauch @Estrauch3]

We are excited to post our most recent manuscript. We automated how to stabilize viral surface proteins inspired by decades of immunogen design https://t.co/VEhItyr3d1.

[Eva-Maria Strauch @Estrauch3]

We developed a two-state, two step protocol that carefully evaluates substitutions and stabilizes the prefusion state while discriminating against the postfusion state. Less than a handful of designs need to be tested to find stable proteins, frozen in the prefusion state.