Consider how many infectious agents driving cancer are not identified yet..
One of the largest PREVENTABLE causes !
Global burden of cancer attributable to infections in 2024: a worldwide incidence analysis - The Lancet Oncology https://t.co/TnE6q9oqbF
I am not able to judge if this novel RNA-repeat arrays associated with a reverse transcriptase is impactful,
but it sure is pretty cool that it was not a human making this discovery 🧩
Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR.
We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use.
Read more: https://t.co/RuEosScSMb
Patients (i.e. aunties, fathers, toddler sons, neighbours, favourite teachers, talented teens) are dying waiting for a new medicine/vaccine.
How to solve the high cost, complexity, and regulatory friction of starting and running Phase 1 (first-in-human) trials?
Support standardized templates so academic centers and startups can open trials without multimillion overhead.
And as icing on the cake:
Create accountability for avoidable delays: patients progress/die while trials stall!) comparable to the existing scrutiny of safety incidents.
This is exactly the kind of innovation that will help solve staffing shortages and improve the patient experience.
Aletta — the world’s first autonomous robotic phlebotomy device.
👏👏👏
https://t.co/dhSfB7Y6cc
"Eliminating cancer mortality generates $197 trillion in economic benefits over 35 years, corresponding to:
($16,282 per American per year),
or
($41,684 per American household per year)".
3/3
3. Sequencing of thousands more species, strains, or individuals within species, and environmental / clinical samples for pathogen surveillance and host–microbe interactions.
4. Improved models that predict variant effects, gene regulation, and phenotypes.
2/3
This could
1. Increase statistical power for genome-wide association studies, rare-variant discovery.
2. Improve understanding of tumor evolution, heterogeneity, and therapy resistance.
High-sensitivity detection in liquid biopsies or minimal residual disease monitoring.
Luxuries that don’t look like luxuries, but are:
1. Having your mom alive
2. Taking hot showers
3. Good health
4. Mental, emotional, and spiritual peace
5. Mild days. Not too cold, not too hot
6. Good food
7. Enjoying coffee in the morning
8. A good night's sleep
9. Clean air to breathe
10. Time to yourself without obligations