Fanglei Xue

AI for science | Protein Design | Drug Discovery

[Fanglei Xue @FangleiXue]

@GabriCorso Awesome! Thanks! I beleive that will be a popular benchmark in the feild, can not wait to evaluate on that! (for a background context, inspired by boltz-2, we did similarity thing extending the model to other modalities)

[Fanglei Xue @FangleiXue]

@sokrypton Amazing, how does the jax version handle the triangle attention, the weithts are 100% compatible to the jax flash attention kernal? Otherwise the speed should be similar to pytorch.compile?

[Fanglei Xue @FangleiXue]

@sokrypton @MoAlQuraishi It might be easier to use openfold3 dataloader and train the jax model directly

[Fanglei Xue @FangleiXue]

After Sergey's talk, I decided to open a twitter account to discuss science. Let's start with the first purely deep-learning designed beta barrels!

[Annika Philomin @AnnikaPhilomin]

Our preprint is out! We present the first generative pipeline for the de novo design of asymmetric β-barrel nanopores, enabling tunable pore geometries and hydrophobic thicknesses.
https://t.co/a4t0XO0GGZ

@ria_sonigra @sagardipm @lyjjj12138 @FangleiXue