Kicking of the new year with our first publication: Our paper dealing with FEM1B-recruiting HDAC #PROTACs is online in #JMedChem@ACSBioMed. We noticed selective HDAC1-3 degradation. Congrats to Felix @fellerflix, Irina, Martina, Heiko, Svenja and Maria! https://t.co/Uj8GEXa487
Let´s continue our E3 ligase hopping party! Second stop: DCAF11. The switch from a CRBN to a DCAF11 recruiter converts a selective HDAC6 PROTAC into a pan-degrader. Congrats to first author Felix @fellerflix and my coworkers Heiko, Martina, Irina & Maria! https://t.co/U7W8q1QV7y
Let´s get the E3 ligase hopping party started with our first stop: FEM1B! Huge congrats to Felix for leading this project from start to finish, and shoutout to Irina, Martina, Heiko, Svenja, and Maria for their amazing contributions! 💪👏 @fellerflix
- https://t.co/8iXt95Cwog