Published today, Vascular Contributions to Cognitive Impairment (VCID) and Brain Health: Clinical Update and Mechanistic Considerations.
This paper proposes that multi-mechanistic origins of VCID and time-appropriate interventions that complement VRFs modification are important to maintaining brain health and preserving cognitive function across the lifespan.
📷 Conceptual diagram of vascular contributions to age-related cognitive decline and worsening brain health.
The source, because no one bothers these days...:
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins https://t.co/eWXII31YwZ
Jean-Martin Charcot was born in Paris on 29 November 1825. @ajlees marks the bicentenary of Charcot's birth by reflecting on how his scientific legacy continues to shape neurology today. https://t.co/ExO6Vy9Hny
Papers like this which demonstrate that alpha synuclein can act potently as prions, are exactly why you need to have proportionate safety measures in labs doing this kind of work. If you work on this and don’t have safety measures ask why! Great paper btw. https://t.co/qoRaVNLdVh
Check out our new resource paper @CellStemCell, where we present a brain organoid atlas of human neurodevelopmental disorders. Surprising was that nearly all patients had abnormal organoids. The challenge was aligning defects to clinical. https://t.co/0YtGTd4Dwb
Today, I teach the (graduate) kids about long-term memory. I'm bringing along my 3D print of HM's brain, made from post-mortem histology. #neuroscience
The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation | Science Advances https://t.co/pZtMH3mOkX
Excited to share our @CurrentBiology Primer written with @AudreyChagnot in the Brain-Body Interactions special issue!
We discuss how the BBB works, what happens when it breaks down, and why this matters for brain and body health.
@UKDRI@TheBHF
https://t.co/QnwkVuHEWh
An amazing collection of brain-body interaction articles in this special issue. Love the beautiful vagus nerve on the cover by Andreas Vesalius https://t.co/K1El0JuJDX