Fernando Meneses

Hola, soy Fernando Meneses Teràn, cardiòlogo clìnico e internista ecuatoriano,investigador sobre factores de riesgo cardiovascular.

[Fernando Meneses @fernanmeneses]

Aula de ECG - Electrocardiograma https://t.co/rTTzBoeL9d a través de @CardioTeca

[Fernando Meneses @fernanmeneses]

Me he permitido programar en MATLAB la estadística del COVID19 en Ecuador: las curvas observada y esperada de su prevalencia e incidencia, y la tasa de mortalidad, desde el 29/02/2020 hasta el 02/04/2020, con los datos proporcionados por la web de la Universidad de Johns Hopkins

[Fernando Meneses @fernanmeneses]

Tratamiento esperanzador para el COVID19

[Fernando Meneses @fernanmeneses]

¿What is the physiological plasma concentration of LDL cholesterol?
The receptor binds LDL optimally when LDL is
present at cholesterol concentration of 2.5 mg/dl,and there is 10 to 1 gradient of plasma/interstitial fluid concentrations of LDL. So,25 mg/dl is the answer.

[Fernando Meneses @fernanmeneses]

COAPT and MITRA-FR (different results): different sample sizes and operator experience; longer follow-up, high selectivity of patients, randomization to mitraclip only after optimum optimal medical therapy,higher EROA or lower end-diastolic volume left ventricle in COAPT.

[Fernando Meneses @fernanmeneses]

On the 19th of September 1991, the naturally mummified body of
the Iceman, also referred to as “Ötzi”, was discovered in the Ötztal Alps
at an altitude of 3210 m. The glacier mummy lived around 3300 BCE
and was approximately 40–50 years old when he died in the high alpine
area

[Fernando Meneses @fernanmeneses]

@ACCinTouch @JACCJournals Congratulations to editors, authors and reviewers of JACC, mainly to its chief editor, Dr. Valentin Fuster.

[Fernando Meneses @fernanmeneses]

¿Are the new oral anticoagulants agents, associated with dual antiplatelet therapy, safe and effective in acute coronary syndromes, with or without atrial fibrillation?...Increased risk of clinically significant bleeding, whereas only a modest reduction in MACE was achieved

[Fernando Meneses @fernanmeneses]

¿Are the new oral anticoagulants agents, associated with dual antiplatelet therapy, safe and effective in acute coronary syndromes?...Positive net clinical benefit only in STEMI.

[Fernando Meneses @fernanmeneses]

Clinical Trials - Hot Lines https://t.co/ZuH1wsAUji

[Fernando Meneses @fernanmeneses]

Results of observational study,pooled analysis,editorial comentary will generate new controversy with AHA and WHS about relationship between salt and CVD. How to resolve it?...We have to design and execute event-based prospective, random.clinical trial in controlled environment

[Fernando Meneses @fernanmeneses]

¿Is metabolically healthy obese really healthy? 1) Results of 2 meta-analysis of prospective cohort studies (22 studies). 2) Results of cohort of 3.5 million individuals, 18 years of age or older and initially free of cardiovascular disease.

[Fernando Meneses @fernanmeneses]

¿What is relationship btw obesity, abdom. obesity and risk of blood pressure?..First meta-analysis cohort studies:Positive association between risk HTN and BMI, WC and WHR (50%, 25%, and 27% increase in relative
risk in BMI (per 5 units),WC (per 10 cm), and WHR (per 0.1 unit))

[Fernando Meneses @fernanmeneses]

New target for inhibition of NLRP3 inflammosome,which is activated in response to cell debris during acute MI. This strategy could act through the inhibition of CMPK2 protein,which promotes mitochondrial DNA
https://t.co/wg6xKuQE5v could reduce myocardial infarction size.

[Fernando Meneses @fernanmeneses]

POINT: Asp.+Clopid.reduce major ischemic events at the expense of an increase in major hemorrhage at 90 days, vs Asp. alone (Minor Stroke or TIA).Analysis of events with similar clinical impact shows increase of net clinical benefit of aspirin+clopidogrel https://t.co/Xh7Vz7eIGM

[Fernando Meneses @fernanmeneses]

¿What is the evidence for that AHA/ACC has adopted the new blood pressure target of less than 130/80 mm Hg?

[Fernando Meneses @fernanmeneses]

¿What is the evidence for that AHA/ACC has adopted the new blood pressure target of less than 130/80 mm Hg?

[Fernando Meneses @fernanmeneses]

A new efficient analysis to assess the net clinical benefit of efficacy and safety in randomized studies of antithrombotic or antiplatelet therapy after ACS, which takes into account events with similar clinical impact. Analysis of ATLAS ACS 2-TIMI 51 trial.

[Fernando Meneses @fernanmeneses]

POST SCD Study in San Francisco: Of 525 autopsied sudden cardiac deaths, 40 % were non-cardiac deaths, 56 % were sudden arrhythmic deaths (SADs). 98 % of SADs had structural heart disease, mainly CAD.