@AJWPharm@pwierusz Coming out of twitter hibernation to state we still need to identify methods to ensure reasonably fast time to therapeutic levels of anticoagulation and empiric bivalirudin dosing can be challenging. The best way to get more data is for people to use bival and share results
@Cait_Centra We still use heparin for a few reasons but chiefly given my center’s inability to use monitoring other than PTT for bival which anecdotally has been problematic in this population. We’re looking at a subset of data from our PGY2 current project what our TTR/time to therapeutic is
We're recruiting for a PGY2 cardiology pharmacy resident @TuftsMedicalCtr for next year! We have a virtual open house and info session on 11/28 from 5-6PM EST via Zoom. We have a great and supportive team! Come find out more next week
https://t.co/Qpi6OQJwuH Tufts is hiring a Cardiology Clinical Pharmacist! Daily rounding with the general cardiology floor team with ops coverage of floor EP and CT surg service. Busy cath lab, PGY2 cards and PGY1 precepting, and a great cards pharm team! Link below! @accpcardprn
@accpcardprn@ADan_osine 1. Graphic looks awesome!
2. I have been WAITING to try this strategy out for a refractory diuretic resistant patient down to 4/5th line therapy but haven’t done it. Who are people using this for?
@pelotonian Been playing for 13 years and finally had a top 10 overall finish! Got lucky picking the right group of GC guys. Appreciate the previews as always
@accpcardprn@juheek10 Great review @juheek10! Guidelines recommend against routine periop drug level monitoring for DOACs - we don't routinely do it but have for emergent surgery similar to peri-CABG PRU monitoring for antiplatelets. What apix/riva drug levels are people shooting for?
@AJWPharm Changes in FXaI drug levels are important when amplified to the level of a larger population. Recent internal MUE here showed patients on FXaI who bled and had supratherapeutic drug levels that 50% were taking 3a4 or pgp inhibitors. Not surprising that the opposite is also true!
@accpcardprn @chfpharmd @ACCinTouch Missing dobutamine on the daily. Stuck with dopa/epi frequently for inotropy or LV vent in cardiogenic shock unless perfusing kidneys enough to clear milrinone in a reasonable amount of time. Bonus: our providers now know the dose-dependent pharmacology of dopamine super well now
@accpcritprn@ACCP@pwierusz@PharmDtotheLAD@Phar_em_D Our practice is to leave vaso as the last pressor following CPB, and double advantage in patients with high TPG. Don't underestimate the role of adequate endogenous vasopressin preop also. Avoiding RAAS blockade in the 48h prior to CPB will help prevent 2° vasopressin deficiency
@accpcardprn Depends on a few things including PVR, renal clearance, and anticipated duration. Tend to lean towards dobutamine as first inotrope for faster on/off and more freedom to adjust SVR. Also curious if anyone actually has preference for one agent with respect to ventricular ectopy