Carb ingestion is not essential for life. The body can make glucose naturally from protein or use it’s stored ketones/fats for energy. Constant insulin release/resistance = shunting of incoming energy: slow tissue starvation in the midst of plenty.
Probably the most important graph for health, ever.
Insulin resistance predicts age-related diseases.
>200 healthy people tested for insulin resistance.
After 6 years, no one in lowest third got heart disease, stroke, cancer, hypertension, or diabetes.
I'm a cardiologist. I've spent twenty years as the person patients trust to interpret their bodies. And I need to tell you something that most physicians won't say out loud:
AI is about to change the power dynamic between you and your doctor. Forever.
Four days ago, OpenAI's o3 model diagnosed 18 children with rare diseases that the best human specialists at Boston Children's Hospital couldn't solve — some after nearly twenty years of searching. Published in the New England Journal of Medicine.
Two weeks ago, WashU researchers proved that nine routine blood markers can calculate your biological age — and predict cancer risk years before any tumor forms. A free calculator. Available to anyone.
Last month, AI-enhanced coronary CT angiography detected inflamed arteries in patients whose standard stress tests said "normal." Patients who would have gone home reassured and wrong.
The pattern is unmistakable. The tools that used to require a specialist, a referral, a three-month wait, and a $400 copay are migrating into your phone, your bloodwork portal, and your own hands.
And I'm watching something in my practice I never expected.
Patients are walking in more informed than some of the residents I trained. They've run their PhenoAge score. They know their ApoB. They've read the study about Lp(a) before I've had time to bring it up. They come with questions so specific that the conversation starts at a level it took me years of training to reach.
This used to threaten physicians. It shouldn't. It should liberate us.
Because here's the truth about the old model: a 15-minute appointment where your doctor runs a basic metabolic panel, glances at the numbers, says "looks fine," and sends you home — that model was never good enough. It was just all we had. It missed 75% of future heart attacks. It caught cancer late. It told women with microvascular disease they had anxiety. It filed children with rare diseases as "unsolvable."
AI doesn't replace the physician. I've said this before and I mean it — the human moment, the clinical judgment, the hand on the shoulder when the diagnosis lands — that's irreplaceable.
But AI does something the old model never could: it gives you the ability to see inside your own biology with a depth and speed that was impossible a decade ago. To track your own numbers. To calculate your own biological age. To bring data to your doctor that elevates the conversation from "am I sick?" to "where exactly am I heading, and what do we do about it?"
The patient who walks in with their ApoB, their Lp(a), their hsCRP, their PhenoAge calculation, and a list of questions from the latest research — that patient doesn't threaten me.
That patient is the easiest person in my practice to keep alive.
Because they've already done the one thing most patients never do: they stopped waiting for permission to understand their own body.
I went into medicine because I wanted to help people live longer. What I've learned is that the patients who live longest are the ones who took ownership — not of my job, but of their own data, their own questions, and their own decisions.
The tools are here. The research is published. The calculators are free. The blood tests cost less than a dinner out.
You don't need to wait for your annual physical to find out what's happening inside you. You don't need permission to understand your own biology. And you don't need to accept "looks fine" from anyone — including me — when the science offers a deeper answer.
The revolution isn't coming. It's in your pocket. In your patient portal. In the published studies you can read yourself.
The only question left is whether you'll use it — or keep waiting for someone to tell you it's time.
Your body. Your data. Your life.
Take ownership. Your future self is counting on it.
The opioid crisis was (is) real. It gutted us. It made us wary. But we built an entire culture of disbelief in its wake.
A culture where real pain is minimized, doubted, ridiculed, or criminalized.
And it's rotting us from the inside out.
@BowTiedVitamins In kidney dysfunction, Mg taken chronically, hypermagnesemia can happen (witnessed).
If no kidney disease, Mg toxicity nearly nonexistent unless drug interactions predispose.
In premature labor, Mg 4 gm IV x1 followed by 2gm/hr =standard. Yes, GRAMS
@ZsoltNagy7@ChrisPalmerMD You are changing the topic.
I never mentioned reversal.
You seem to be thinking in black and white terms, up or down of insulin resistance.
I think of insulin resistance as a teeter-totter on forklift going uphill as one ages.
Does this help?
@ZsoltNagy7@ChrisPalmerMD In practice 35 years. Nothing new, IR is finally getting more attention.
IR causes are multifaceted; science is ever teasing out the intricacies.
Point is, IR isn’t a have/have not, but a continuum scale. Everyone’s balance can be disrupted
@ZsoltNagy7@ChrisPalmerMD Ever see young healthy patients get acutely ill, end up in critical care, and on an insulin drip? Check. Not as uncommon as you might think.
Also have seen Gestational diabetics lose sleep for 1 night affecting their insulin needs the next 24-48hrs.
Unless you want Beyond Meat 🤢 👀
Regenerative ag is sustainable w NO fertilizers/feed.
Return to heritage livestock (hardy, relatively disease-free + not bred for just fast growth on feed).
Back regen ag! @untappedgrowth
https://t.co/E5OfWuHkVx
@RepThomasMassie China stopped exporting fertilizers until Q2. Russia too. Now Belarus stopped Potash via force majeure. Bayer can't deliver enough pesticides.
There are two pandemics going on, avian flu and swine fever. B
I could go on.
https://t.co/wjNKqhRfdk
Agreed. I have met with him as well, several times, and I visited in OK. Talked w the locals. They are behind him - in spades.
I was never solicited, found him on my own.
His heart is pure. This isn’t about money, it’s preserving US food sovereignty.
@Cornwatch21@untappedgrowth Unless you’re in the trenches, it’s hard to see what’s happening to local farmers pinched HARD by the major meat packers, increasing restrictions and constraints making it unprofitable.
America is losing it’s heartland to conglomerates.