Brian

Stocks, Tech, Music, Father, Liberal, Family & Friends, Taekwondo, Kravmaga, Pro Farmers, psychedelics

[Brian @freeliners1]

@Graham__Hancock I love reading your books on psychedelics and ancient history.
I share your view on the origins of various civilizations. Thank you!!

[Brian @freeliners1]

@ExposingEvil704 What happened with the kids after this interview?

[WhatdoIknow @Earstohearyou]

Matter is stable GEOMETRY made visible through resonance within an OSCILLATING field of motion.
https://t.co/wmTyha7eyZ

[Dr. Rhonda Patrick @foundmyfitness]

New episode with Dr. Steve Horvath (@prof_horvath), a pioneer in the field of epigenetic aging clocks.

Steve developed the original Horvath clock, one of the first tools to show that DNA methylation carries a remarkably reliable signal of aging across human tissues.

In this episode, he explains what biological clocks actually measure, why different clocks can disagree, and how to interpret a biological-age result without treating it like a literal lifespan forecast.

We talk about chronological age vs. biological age, and we also get into the intervention evidence on exercise and VO2 max, calorie restriction, omega-3s, vitamin D, multivitamins, and weight loss/GLP-1 therapy, among other topics!

The big theme is that biological clocks can be useful dashboards, but they are not diagnoses, fortune-telling tools, or proof that one supplement has reversed aging. This was Steve's second appearance on the podcast and he did not disappoint. You won't want to miss this episode.

Links to the episode on all platforms in the comments below.

Timestamps:
0:00 - Introduction
1:59 - Biological vs. chronological age
7:33 - Why one clock isn't enough
13:16 - PhenoAge vs. GrimAge
15:21 - GrimAge & mortality risk
19:04 - Epigenome as stress memory
23:02 - Can stress be inherited?
25:06 - Why clocks fail in sperm
26:30 - Can lifestyle reverse GrimAge?
28:18 - DunedinPACE as an odometer
32:20 - Judging longevity interventions
34:41 - Clocks as mortality surrogates
38:28 - Most validated interventions
41:25 - 5 years younger in 7 months?
45:43 - Can GrimAge predict death?
47:30 - Translating GrimAge to lifespan
52:16 - Blind spots of aging clocks
58:20 - More than inflammation
1:00:56 - Young blood, transient effects
1:04:46 - Calorie restriction
1:08:54 - GLP-1 drugs & weight loss
1:12:24 - Can a multivitamin slow aging?
1:21:05 - Omega-3, vitamin D, & exercise
1:28:55 - Removing an aging accelerator
1:31:24 - Vegetables vs. exercise
1:36:58 - Does red meat age you?
1:38:38 - Hard training moves the clock
1:45:59 - Heat as an exercise mimetic
1:47:23 - When cold slows the clock
1:49:48 - Does poor sleep speed aging?
1:51:19 - Can friendship slow aging?
1:57:49 - Are consumer tests worth it?
2:02:46 - Choosing a reliable test
2:07:33 - Different clocks, different lenses
2:12:21 - Can AI build better clocks?
2:13:53 - Partial reprogramming
2:17:47 - What reprogramming can't fix
2:22:37 - Do DNA mutations drive aging?
2:24:53 - The silver bullet problem
2:29:23 - Limits of polygenic risk
2:33:32 - Steve's longevity routine
2:38:05 - How stress affects aging

[Brian @freeliners1]

QNX is already inside a large installed base, and that gives the company something more concrete than the usual AI pitch about software that might someday arrive. Still, the market has not been willing to price BlackBerry as a physical AI play. $BB
https://t.co/3GV2TANEOO

[Brian @freeliners1]

@IAMessential316 I sold $9,22 and bought back at $8,65.
The QNX story is not over jet, it's just the beginning. that's my view on the stock. Longterm $BB

[Brian @freeliners1]

@WerewolfHolding @CNBC Especially what they said about possible 2 Big European contract wins. $BB

[Brian @freeliners1]

@patientinvestor What was said about Bitcoin again? Let me guess, it’s going to the moon? $Bitcoin #Bitcoin

[Larry Conger 🇺🇸 @eMTBrides]

This dude sounds more like Bon Jovi than Bon Jovi sounds like Bon Jovi!!! 😮 Bon Jovi with a tinge of Axle Rose 🥀 via Your Open Circle

[Arielle Scarcella @ArielleScarcell]

Normal old gay guys says young queers are annoying 😂😂😂

[FLAT OUT TRUTH @TheFlatEartherr]

All the ancient civilizations knew of the giants that's once inhabited the earth.

[Brian @freeliners1]

@MeesWijnants Investeer in je gezin en doe ze op een vechtsport. MMA , Kravmaga whatever.
Je moet je zelf kunnen beschermen. Basisvaardigheden voor zelfvertrouwen en fysieke fitheid

[Daniel Hull @hulldaniel67]

Wow what an analogy @QNX_News

https://t.co/OIkcspmMdO

[Ryan Cey @RCEY28]

I had no idea thistle was edible until this video stopped me in my tracks.
Thistles have completely taken over my property for years — I’ve spent more weekends than I can count hacking them down, cursing every prickly inch, and dumping weed killer like they were the enemy.
Then I watched her walk straight into the field, slice a stalk with zero hesitation, peel back the armor, and bite right into the sweet inner core like it’s something she’s done her whole life.
Now I’m staring at the “weeds” in my yard completely differently. Have I been fighting a free wild-food buffet this entire time… or is this one of those things smarter people leave to the pros?
Who here has actually tried eating thistle straight from the field? Drop your stories (and any warnings) below — I might grab a knife tomorrow 🌱🔪

[Veronica, Collagen Scientist 🇵🇱 @celestialbe1ng]

A 91 year old British grandad promoting his granddaughter’s organic coconut oil potato crisp company and it’s the best food commercial I’ve ever seen.

[Brian @freeliners1]

@gainzalgo The QNX story is not over yet, it's just beginning. $BB
Physical AI and Robotics

[Eren Chen @ErenChenAI]

“The next trillion-dollar opportunity is Physical AI and Robotics.”

— Masayoshi Son, CEO of SoftBank, also just became the richest in Asia

[Free Wyckoffs @FreeWyckoffs]

$BB I provided this technical analysis video to members on 1/16/2026.

Wyckoff Methodology and VPA.

Remember I said back in 2023 that QNX would be HUGE for the company? Mark-ups awaiting.

Doubt it.
or
Learn it.

https://t.co/qYRbNZNNCy

[Brian @freeliners1]

Even the Dutch Analists are waking Up! 😉 Advice is Hold ( in Dutch)
BlackBerry $BB
https://t.co/KHXCQXunJb