Ahmed Gaber

Senior AI Engineer @57357 . Biomedical Data Science MSc from @Clemson.

[. @sailorsRest1]

Depictions of ancient Egyptian gardens

[alex peysakhovich @alex_peys]

what is happening here:
claude used existing open source tools and orchestrated them together to do a protein design campaign (with a big guide prompt!)

this is a win for claude because doing this orchestration requires a lot of biological judgement and knowledge

however, the tools are doing A LOT of the lifting here so it is just as important to give credit where it is due to the open source academic community. this is not just typing into claude "hey give me a binder to X" and have it spit out a protein sequence.

this also means that the limitations of these tools need to be thought about, and in particular we know that all of these tools fall down when faced with targets that are outside of the range of their training data (so we can't really design binders against most targets with them)

so... this is cool but you really need to think about it in context

[Ahmed Gaber @Gaborandi88]

Astra, then Fable 5.1
The progress is now faster than what we imagined few years ago.

[leo 🐾 @synthwavedd]

🚨 A successor to Fable 5, likely Fable 5.1, is now being tested for a subset of accounts with "Fable 5" selected on Claude Web, and possibly also Claude Code

Fable 5 also underwent this greyscale testing earlier on the day of its broader release, and Anthropic regularly carry out these tests pre-launch

[Hugging Face @huggingface]

We've just surpassed 3 million models on the Hub 🤗

the community is accelerating towards an open, distributed future where open AI is everywhere, for everyone 🚀

[Xiaoyin Qu @quxiaoyin]

Dear Dario,
1. If Claude can cure cancer to save people like your dad, why should we "pace the progress"? Does that mean more people with Hepatitis C will die?
2. If Fable is so cyber-capable that it must be restricted, why are its safeguards too dumb to distinguish cyber defense from cyber offense prompts? When Hugging Face was under attack, why did Fable refuse to help the defenders?
3. We’re glad you want AI to cure cancer. Why is it OK for Claude to force 30-day data retention on pharma's own data and start competing firms but NOT OK (IP theft) if others distill Claude's data?
4. You’ve said advanced models can recognize when they’re being tested and change their behavior accordingly. So why is government(or anyone) able to design the most thorough test before every model launch? Would that just encourage manipulative models?
It seems that every one of your “safety” proposals seems to end the same way: Anthropic gets more leverage, ordinary users get less access, customers pay higher costs, and competitors bear higher regulatory costs, maybe people are not distrusting AI, they are distrusting your approaches with AI.

[Ahmed Gaber @Gaborandi88]

Still my fav

[Matt Dancho (Business Science) @mdancho84]

Type 1 and Type 2 errors are confusing. In 3 minutes, I'll demolish your confusion. Let's dive in. 🧵

[Zafar Mirzo @zafarmirzo]

Why Did Death Become a Necessary Condition for Evolution — and Will Humanity Still Need It in the Future?
Death created humanity — so that humanity might one day defy death itself.
The Role of Death in Evolution
Adaptive traits arise through mutations and genetic recombination, with the resulting variations expressed in offspring. The more frequently generations turn over, the more opportunities there are for beneficial changes to arise and be selected, and for genetic diversity to be preserved. From an evolutionary standpoint, what matters is not the age of an individual but the frequency of reproductive cycles: the shorter these cycles are, the greater the likelihood that advantageous variations will arise. Excessive longevity or biological immortality in individuals would therefore slow the evolution of species.
Mortality enables natural selection: poorly adapted individuals are eliminated, giving way to more viable ones. Without it, disadvantageous genetic variants would accumulate, reducing the stability of populations.
Death also sustains the cycling of matter and the flow of energy required for ecosystem stability.
A limited lifespan prevents overpopulation and excessive competition for resources within a species.
If individuals were immortal, their populations would grow uncontrollably, leading to resource depletion, reduced or halted reproduction, and, consequently, the collapse of populations when environmental conditions changed.
Thus, death is a necessary condition for the creative process of evolution: it accelerates generational turnover and thereby increases the opportunities for mutations to arise, sustains diversity, prevents overpopulation, and makes natural selection possible.
Without it, life would lose its flexibility, exhaust its resources, and perish with the first changes in environmental conditions.
Yes, death was an instrument of evolution, refining life to the point at which intelligence and civilization could arise.
But now humanity itself must consciously carry evolution forward — and liberate life from the dominion of death.

[Ahmed Gaber @Gaborandi88]

ومفيش حاجه اسمها منحه التقديم عليها سهل، مكانش حد غلب وكله قدم، الموضوع عاوز تعب وصبر وهدوء وتبقى عارف انت عاوز ايه من الأول.
وبالتوفيق

[Ahmed Gaber @Gaborandi88]

منحه إيراسماس فاتحه
التقديم فيها ممكن يكون ثعبانى شويه، بس فرصه حلوه

https://t.co/9SORbsDDFF

[Ahmed Gaber @Gaborandi88]

Daimn
This is sick

[Maciej Dobrodziej @M_Dobrodziej]

Warszawa, której nie ma. Lata 30.

Zamroziłem całą ulicę i przeleciałem przez nią kamerą - między przechodniami, tramwajem, szyldami.

Seedance 2.5, jedno archiwalne zdjęcie. Prompt w komentarzu.

[Ahmed Gaber @Gaborandi88]

@MichaelAzmy Egypt be like: normal day!, what does it mean ?

[Mannay 🌹 @mannay]

You can just draw faces with javascript

// coding doodles

[Ahmed Gaber @Gaborandi88]

@scaling01 One Kidney per million tokens

[Ahmed Gaber @Gaborandi88]

How many kidneys would it take for a one week subscription!!

[OpenAI @OpenAI]

Previewing Ultrafast mode: GPT-5.6 Sol at up to 14x the speed.

Launching first in the OpenAI API to a select group of customers with expanded access to more businesses as capacity grows.

[ᴍᴇɴᴀ ♑︎ @menaox2]

شكرا للشخص اللي اكتشف الـ gif هذا وخلاه يحتل تايمي

[Alexander Panfilov @kotekjedi_ml]

We can finally talk about it:

We found a way to extract hidden reasoning of frontier models using a vulnerability in the APIs of every frontier AI company.

We verified that our reasoning token count matches billed API thinking tokens 1:1 for most of the prompts we queried.

[Ahmed Gaber @Gaborandi88]

الفيس بوك مفيهوش خبر واحد عدل. أقسم بالله نكد بس.

[Ahmed Gaber @Gaborandi88]

@thsottiaux Also, ‘computer-use’ in claude paralyze my desktop and i can’t use anything else while it is working, but codex doesn’t

[Ahmed Gaber @Gaborandi88]

@thsottiaux Claude ‘opus 5’ just ruined my 6 months work in 15 minutes. Deleted it all because i asked to it remove the unnecessary files which already has a different path. 🦭🦭🦭 (luckily i had a backup)