Gregory Eschenauer

Infectious Diseases Pharmacist and Clinical Professor @umichpharmacy

[Gregory Eschenauer @geschena]

Yes! Our phenomenal BLAES service: https://t.co/qcTqCGgzZi

[Gregory Eschenauer @geschena]

@alexis13booker @elisevk14 @coachfitz1973 @TeamHuddleBball @R_Photography1 @elisevk14 👋!!

[Gregory Eschenauer @geschena]

@RimaForAAPS Obviously, I think Rima is the best, but I may be a smidge biased. However, I can absolutely attest to her long-standing dedication to these issues. She's also a proven collaborator and team player. Perfect for this role.

[Gregory Eschenauer @geschena]

@RimaPharmD You'll get no like from me on this one!

[Gregory Eschenauer @geschena]

@jpogue1 And as far as @jpogue1, can you imagine having access to THAT brain during a pandemic when rapid-fire critical, nuanced literature evaluation is absolutely essential? However highly you think of him, your bar is still way too low.

[Gregory Eschenauer @geschena]

@jpogue1 We all know how intense/bewildering/exhausting/etc. it was to develop and maintain COVID guidelines for our institutions over the past year +; can you imagine NIH guidelines? Can't thank @IDPharmProf enough, who was there from the beginning and helped us all.

[Gregory Eschenauer @geschena]

@DHpharmd @OncIDPharmd @umichmedicine @MMAbxStew @maitkencancerhx Oooh, who cares about Jordan, what I really want to know is: which one of us is Rodman?

[Gregory Eschenauer @geschena]

@RimaPharmD @OncIDPharmd @umichmedicine @MMAbxStew @maitkencancerhx So excited!

[Gregory Eschenauer @geschena]

@NikkiTranID @IDRenaissanceMD @not_that_CDC did this to me on my first day of staffing training as a resident. I 100% fell for it.

[Gregory Eschenauer @geschena]

@RimaPharmD @UMichPharmacy @riteaid This team went from identifying vaccine that needed to be used by Monday on Saturday PM, to setting up this clinic, to vaccinating >125 members of the community within 24hrs. Astonishing.

[Gregory Eschenauer @geschena]

@DosingMatters @UMichPharmacy You know what your running partner was doing after that 5k...STILL RUNNING. I saw him with my kids at the Arb! Amazing...

[Gregory Eschenauer @geschena]

@Tejal_N_Gandhi @jbaang @zhoushiweis @jpogue1 @MeganKlatt3 And Nick Dillman, our Peds stewardship pharmacist, who somehow designed and runs that website in his 'spare time'!

[Gregory Eschenauer @geschena]

@TheIDApprentice @UICPharm @UMichPharmacy So excited!!

[Gregory Eschenauer @geschena]

@ClancyNeil Agreed. But what is that patient population? I can't define it in anything approaching 'easy to use' (or at all). Even machine learning algorithm (for candidemia) could only hit 5% positivity (Bhavani Crit Care Med 2020).

[Gregory Eschenauer @geschena]

@ClancyNeil Right, but that's using a test to stop use that should have never started in the first place. Not arguing that's not real-life, but then the effort should be spent stopping 'fly by seat' use, not adding lab with lots of false positives that gets you into trouble.

[Gregory Eschenauer @geschena]

@ClancyNeil This is also informed by things like a.) MSG-01 algorithm is complicated but still misses half of IC cases b.) How much is SICU IAC outcome modified by (early) AFs? Most important time-sensitive intervention is source control, which also gets us cultures...

[Gregory Eschenauer @geschena]

@ClancyNeil Agree re: NPV, but don't share your optimism about identifying a practical algorithm (+ BDG/T2) that improves outcome of ICU pts. Love to be proven wrong, but literature to date leaves me pessimistic.

[Gregory Eschenauer @geschena]

@ClancyNeil I'd argue that RCTs that identified patients with that (5%-15%) threshold, and tested early antifungals, didn't show a pronounced benefit (Knitsch CID 2015; Schuster Ann Intern Med 2008; MSG-01).

[Gregory Eschenauer @geschena]

@ClancyNeil But are EMPIRICUS 'high risk' criteria practical? Complicated rules don't work outside RCTs. From what I can tell it involves multi-site colonization assessment (mean 5 sites sampled at inclusion- eTable 1).

[Gregory Eschenauer @geschena]

@millerjtm @umichmedicine @UMichPharmacy @SCCM The dude!! Man I miss him...