Logan Bartholomew

UC Berkeley Organic Chemistry PhD @SarpongGroup from KY. NSF GRFP. BS, GWU, 2020. Sometime baker, guitarist, delusional golfer, and skiing addict.

[Logan Bartholomew @gloganb]

This project was a ton of fun to put together and wouldn’t have been possible without the tremendous efforts of this team. Check out our now-published cheminformatic platform for skeletal edit development prioritization below!

https://t.co/4ZVAjsFmC3

[Sarpong Group @SarpongGroup]

Congrats to @gloganb & collaborators @lucaskaras1 (@Sigman_Lab) & Reilly & @Charles_chem (Merck) on the publication of our work on a cheminformatic analysis of core-atom transformations in pharmaceutically relevant heteroaromatics in J. Med. Chem.

https://t.co/T3LqAnpSV0

[Sarpong Group @SarpongGroup]

Congrats to @gloganb, @SojungKim20, Yusuke and collaborators @BarnerKowollik, @GileadSciences, @Merck on our indazole to benzimidazole conversion  https://t.co/qiry103DEp coordinated with @LeonoriLab  https://t.co/Jugs3Nm4aY

[Logan Bartholomew @gloganb]

This work wouldn’t be possible without the tremendous efforts of @SojungKim20, Yusuke Oyamada, @JustinJurczyk at @GileadSciences, @Charles_chem at @Merck, and the @BarnerKowollik group. I can’t thank these collaborators enough. (2/2)

[Logan Bartholomew @gloganb]

Our study detailing indazole-to-benzimidazole phototransposition is out now in @angew_chem together with related work from @LeonoriLab!

This has been a fun project to lead, and it’s been my privilege to work with this awesome team. Read below! (1/2)

https://t.co/H9VQewlqqY

[Sojung Kim @SojungKim20]

To round out our work on these photomediated ring contractions of saturated heterocycles, I'm excited to share this collaborative story about uncovering interesting enantioselectivity trends in this system, out now in @J_A_C_S!

[Brandon Wright @B_randonwright]

The final chapter of my PhD with @SarpongGroup at @UCB_Chemistry is published! Check out our full story of how we approached the synthesis of Daphniphyllum alkaloids inspired by molecular complexity scoring, out now in @J_A_C_S 🎉 https://t.co/BfoKhIqL26

[Logan Bartholomew @gloganb]

We’re excited to share our quantitative assessment of the potential impact of skeletal edits, now on ChemRxiv! This cheminformatic platform was developed with @lucaskaras1 from @Sigman_Lab and Reilly Eason & @Charles_chem at #MerckChemistry.

https://t.co/8U3mqcQ0PC

[Brandon Wright @B_randonwright]

Ever thought about quantifying molecular complexity? We wrote a Perspective on how modeling this fascinating concept can lead to new insights in synthetic chemistry. Check it out in @NatRevChem! 🎉

@SarpongGroup

https://t.co/LIlqiI1cuf

[Paul Sinclair @Paul_P82]

My total synthesis of baphicacanthcusine A is out now in @angew_chem. It has been a fascinating journey learning about these unique molecules and I’m really proud to tell this story! https://t.co/R5eElTDEai

[Sojung Kim @SojungKim20]

Our investigation into the photomediated ring contraction of saturated heterocycles is out in @J_A_C_S! Excited to finally share my inaugural 1st author, multi-part story that blends synthesis, mechanistic & wavelength-dependent insight, and computations.
https://t.co/dVqUQxcmyS

[Logan Bartholomew @gloganb]

Guilty as charged

[Dr. Ortiz, Process Chemistry-er @KCGOrtiz]

F*** it. Using "editing" in the title of my next paper.

Suzuki Rxn? Editing via C-C Bond Formation and Halogen/Boron Deletion.

3+2? Editing via strategic rearrangement of electrons to form a cycle.

Dearomatization of Pyridinium? Editing via the removal of aromaticity.

[J. Am. Chem. Soc. @J_A_C_S]

14N to 15N Isotopic Exchange of Nitrogen Heteroaromatics through Skeletal Editing | Journal of the American Chemical Society @UUtah @UtahChemistry @UCBerkeley @UCB_Chemistry @Sigman_Lab @SarpongGroup #Hetarenes #Skeletal #Editing @TotalSyntheses https://t.co/Icsimaxe5a

[Logan Bartholomew @gloganb]

Our azine N-isotope exchange is out now in @J_A_C_S! Excited to share this story with a few twists in the @SarpongGroup with the @Sigman_Lab and @Charles_chem from #MerckChemistry. Big thanks to @SamLKraus, @lucaskaras1, and this awesome team.

https://t.co/LToVrNn6tK

[Sarpong Group @SarpongGroup]

Congrats to @gloganb , @SamLKraus and our collaborators at #Merckchemistry and the @Sigman_Lab on the publication of our work on 14N to 15N exchange in azines in JACS!

https://t.co/RDY3KMqlaE

[L.-C. Campeau Ph.D. @DrLCsquare]

Great day meeting at @UCB_Chemistry for the #MerckChemistry lecture yesterday. Enjoyed the panel discussion in the AM with students!

[Sarpong Group @SarpongGroup]

Fourth year @gloganb, placed 2nd in the poster session for his great poster on his
recent 14N-to-15N skeletal edit of nitrogen heteroaromatics work. Congrats Logan! We’re so proud of you! 5/5

[Andy McNally @AndyMcNally367]

15N Incorporation into pyridines via NTf-Zincke imine intermediates now on @ChemRxiv . Congrats to Hillary, David, Marie, Kaila, and Jeff from my lab: https://t.co/0rIJ8Mx8fH

See related work from @SarpongGroup @Sigman_Lab/ Smith/Feuillastre-Audisio

[Logan Bartholomew @gloganb]

Grateful to have been a part of this awesome team and work with #MerckChemistry and the @Sigman_Lab! Excited to share my new first author paper on an isotopic labeling strategy for nitrogen heteroaromatics using skeletal editing. Check it out on ChemRxiv: https://t.co/RziYdjnyYk.

[Sarpong Group @SarpongGroup]

Swap it out! Congrats @gloganb and @SamLKraus with @Charles_chem (#MerckChemistry) and @lucaskaras1 (@Sigman_Lab) on a 14N-to-15N skeletal edit of nitrogen heteroaromatics (https://t.co/BGKZaMTcxk). Great related works from Joel Smith, Feuillastre/Audisio, and @AndyMcNally367!

[Logan Bartholomew @gloganb]

@BagPhos @SarpongGroup @Sigman_Lab @Charles_chem @ChemRxiv Thanks for sharing!

[J. Am. Chem. Soc. @J_A_C_S]

Skeletal Editing of Pyrimidines to Pyrazoles by Formal Carbon Deletion @SarpongGroup @UCBerkeley @UCB_Chemistry @TotalSynthesis @TotalSyntheses #Editing #Pyrimidines #Pyrazoles #Carbon #Deletion https://t.co/66SfIpo3v7