DY

[DY @grainfire]

@andrewpannu Sleuth

[Caleb Watney @calebwatney]

25-40% of clinical trial costs come from an excessive quality-check process that the FDA itself has recommended against for over a decade.

Great piece from a former FDA official on why the whole system is stuck in a "too big to fail" loop.
https://t.co/yX4gNVy04k

[Simular @SimularAI]

1/ Wait, Bigfoot figured out how to run a startup without drowning in multitasking 👀

It found 𝗦𝗶𝗺𝘂𝗹𝗮𝗿 𝗣𝗿𝗼, the world’s first production-grade, computer-use agent that runs thousands of steps without a hiccup - working 24/7 so he didn’t have to.

So how does Simular Pro work?

Most agents use LLMs - great explorers, but flaky when # steps grows; RPAs are stable but rigid. Simular Pro uses 2 agents, maximizing generality & repeatability:

- Neural: explores
- Symbolic: executes

Every action is editable, deterministic code.

[Stephanie Armour @StephArmour1]

Resignation letter of Peter Marks from FDA’s director for the center for biological evaluation and research

[DY @grainfire]

@NotionHQ Forms😀

[Kyverna Therapeutics @Kyverna_Tx]

The @US_FDA has cleared our IND application for refractory, progressive #multiplesclerosis, addressing a need for a new therapeutic paradigm that can potentially result in sustained treatment-free remission & ease risks of long-term toxicities #celltherapy https://t.co/FUZq4X1C7y

[Immuneering Corp @Immuneering]

We believe targeting #RASmutations through the #MAPKpathway is a promising area of #cancer research & #drugdevelopment. Our universal-RAS program aims to target RAS-mutant, advanced solid tumors. using the MAPK pathway. Learn more: https://t.co/9msaIuOamE

[Immuneering Corp @Immuneering]

We are pleased to announce that we have received IND clearance from the FDA for IMM-6-415, paving the way for the initiation of a Phase 1/2a clinical trial for the treatment of advanced RAF or RAS mutant #solidtumors. Learn more: https://t.co/5nrI5D1C2C

[Kyverna Therapeutics @Kyverna_Tx]

Kyverna is developing a fully human anti-CD19 #CART #celltherapy in autologous and allogeneic formats for #AutoimmmuneDisease. Hear more from our Sr. VP and head of research.
https://t.co/AmGck8qXUF
@CGT_Live

[DY @grainfire]

@erlichya @eleventx Very cool!

[DY @grainfire]

Arc's new Max function is brilliant. Can't help but want to clap for them.

[Aspen Neuroscience @AspenNeuro]

We are excited to be presenting at the annual Cell & Gene Meeting on the Mesa this week!

https://t.co/1bal4MnkUD

#CGMesa23 #iPSC #autologous #celltherapy

[DY @grainfire]

@fibery_io Excited about this feature! Will change how interact with the database

[OpenAI @OpenAI]

We’re rolling out web browsing and Plugins to all ChatGPT Plus users over the next week! Moving from alpha to beta, they allow ChatGPT to access the internet and to use 70+ third-party plugins. https://t.co/t4syFUj0fL

[DY @grainfire]

@whyyoutouzhele @get_this_v

[DY @grainfire]

@whyyoutouzhele @SaveMyVideo

[DY @grainfire]

@whyyoutouzhele @GetVideoBot

[jenny mccann @jennyeye]

My 42yr old twin brother died in ITU of COVID-19 last week. He died exactly 4 weeks after testing positive. He was the fittest, healthiest person I know. He was climbing Welsh mountains & wild camping 4 weeks before his death.

[DY @grainfire]

@RoamResearch I have problem creating bracket links this morning (no new page created after [[]] and click on the bracket link do nothing). Is this just me or something going on at the server side?

[DY @grainfire]

Store, Backup and Sync across multiple users and computers and collaborate on files with @OpenDrive. https://t.co/lIdIodv3ol