The Twitter account of the Organic and Biomimetic Chemistry Research Group at Ghent University. At the interface between chemistry and biology since 2002.
We are happy to share our latest work published in @angew_chem, where we showed the effect of photochemically staple #DNA G-Quadruplex and I-Motif structures, boosting up their thermodynamic, topological and metabolic properties.
https://t.co/soWqAiUBRO
Take a look at our paper about a red light-triggered alkylation methodology for sequence-specifically target G-Quadruplex and i-Motif #DNA structures, finally published in #NAR @NAR_Open @AlexManicardi@EnricoCadoni1
https://t.co/9JyW9dtRx9
#G4#Quadruplex#imotif#Chemistry
▶️PubReading [152] - Teaching photosensitizers a new trick: red light-triggered G-quadruplex alkylation by ligand co-localization - E. Cadoni, A. Madder et al https://t.co/s0udRWz3hA 🔊@EnricoCadoni1@AlexManicardi#Gquadruplex#Chemistry#PubReading 🎙️