Hayder Hussein

[Hayder Hussein @h4yder]

@BloodJournal

[ParalympicsGB @ParalympicsGB]

And it's GOOOOOOOLD for Megan Richter! Oooh yes!!

What a morning for the Brits on the bridge.

#ParalympicsGB 🥇#ParaTriathlon

[HaemTRIAL @HaemTRIAL]

Are you a clinician who sees patients with secondary polycythaemia?

Are you frustrated by the lack of an evidence base for treating these patients?

Does your practise differ from your colleagues when treating these patients?

[Hayder Hussein @h4yder]

@MorphologyAmigo @Dr_MSU @nihardesai7 @TalhaBadarMD @PriyaSriRajah @blood_academy @WilsonAndrewDr @BijoyTelivala Ivosidinib is an IDH1 inhibitor, so not applicable here. Enasidinib (IDH2 inhibitor) not a UK option at the moment…a case of treat with what you have…

[Hayder Hussein @h4yder]

@MorphologyAmigo @nihardesai7 NICE TA currently suspended….awaiting regulatory plans from the company…

[Hayder Hussein @h4yder]

@richardbuka @BritSocHaem Drug cost?

[Benlazar S M A @smbenlazar]

Strategies to reduce relapse risk in patients undergoing allogeneic stem cell transplantation for #AML #leusm |British Journal of Haematology | Wiley Online Library https://t.co/lLqqRMeZ8u

[Anas Nasir @BloodScientist]

Chromatin patterns 🧵

[1] How many times have you heard phrases like:
"Fine chromatin"
"Dotted like with a pencil"
"Smooth chromatin"
"Clumped chromatin"
"like a football (some of y'all may call it a soccer ball)"...?

What do they mean and how do you make sense of it all? How does the chromatin relate to the morphology? Let's take a deep dive. 👇

#OnlyCells #Chromatin #BackToBasics

[Hayder Hussein @h4yder]

@MorphologyAmigo @veraghali @NicoGagelmann Heard and read about plateletpharesis but have never had to do it, cytoreduction being the mainstay. Having said that I do know of a case where patient had a count of >3000 and resistant to max dose hydrea, pegasys and ruxolotinib…

[Vidhya Murthy @VidhyaMurthy1]

Excellent presentation by Vaishali o risk factors and outcomes of CAR T manufacturing failure. #ASH2023

[Hayder Hussein @h4yder]

@kungfudoctor I knew you’d be a fan of Q

[Pip Nicolson @PipNicolson]

Very pleased to able to share our latest research on platelet activation in #VITT authored by @richardbuka and @sam_310 from @bhamplateletgrp and @ICVS_UoB published in @BloodJournal yesterday. We show that PF4 itself activates platelets via the TPO receptor c-MPL.

[Hayder Hussein @h4yder]

@ManniMD1 I thought that Sjogren’s is associated with MALT lymphoma which often has an IgM paraprotein. Although by definition this isn’t MGUS…

[Claire Harrison @harrisoncn1]

Super pleased to see that NICE has approved Ruxolitinib for PV in England !! @MPNVoice FDG published today.
Let’s get on and test this drug in the front line as the Mithridate study being run jointly between 🇫🇷 and 🇬🇧 with @jjkiladjian

[Hayder Hussein @h4yder]

@BookshopOTGreen Ah so sorry to hear this, my boys and I loved having the bookshop nearby. Good luck with the next chapter, and hope that it continues to bring happiness to the local area!

[Hayder Hussein @h4yder]

@Existential_Doc Any tips for severe haematuria outside of bladder washouts? Difficult as TxA contraindicated…

[Hayder Hussein @h4yder]

@richardbuka Maybe best place to intervene is at pharmacy/dispensary level. It’s quite a good way of improving prescribing patterns…@nickduncan31?

[Vidhya Murthy @VidhyaMurthy1]

Our first regional AML day. Excellent talks and stimulating discussions.@UhbTeam @FWANDROO @HaemOnc @francescakinse3 @h4yder

[Hayder Hussein @h4yder]

@MorphologyAmigo Have never come across this scenario! Broadly speaking allergies need close scrutiny-thorough history, speak to pharmacy and immunology. ATRA is so crucial though that I’d be likely to press on with it (maybe the dexamethasone cover for differentiation syndrome will ameliorate!)