hari s

epidemiologist
CDC eis
icmr

[Roland Baker @RolandBakerIII]

Evaluating the use of dose-sparing vaccination strategies for Monkeypox: dose-sparing strategies are beneficial provided fractional-dose is >40% of full dose VE (34% absolute VE), projecting 13% - 70% (68% absolute VE) fewer infections (h/t @harisankars1)
https://t.co/GpxPVy7KeZ

[hari s @harisankars1]

@maolesen BA.2.75 prevalence in samples is down to 70%.
XBB is being detected in some 20% of cases. BA.2 subvariant in 7% of cases and prevalence of BA.5 is down to less than 3 %.Last week India detected a BQ.1 infection in a Pune sample.

[Roland Baker @RolandBakerIII]

Genomic accordions may hold the key to Monkeypox Clade IIb's increased transmissibility (H/T @harisankars1)
https://t.co/THXAxYctkF

[Roland Baker @RolandBakerIII]

Evolutionary consequences of delaying intervention for monkeypox: pathogens with R values just above 1, such as monkeypox virus, have a higher probability of evolution during the timeframe in which the number of cases remains low. (H/T @harisankars1)
https://t.co/QaaFTdx2Nk

[Roland Baker @RolandBakerIII]

(1/n) Genomic deletions and rearrangements in monkeypox virus from the 2022 outbreak, USA: three MPXV genomes containing deletions ranging from 2.3 to 15 kb and four genomes containing more complex rearrangements. (H/T @harisankars1)
https://t.co/Y9mkwZo2fH

[Roland Baker @RolandBakerIII]

ICMR performs genome characterization of monkeypox cases, identifies 3 sub-clusters among A.2 lineage in India (H/T @harisankars1)
https://t.co/15oXZNiTPb

[Roland Baker @RolandBakerIII]

Atypical oral presentation of monkeypox virus: A report of two cases from Florence, Italy (H/T @harisankars1)
https://t.co/2T3aAZTbWe

[Roland Baker @RolandBakerIII]

Phylogeny-aware linear B-cell epitope predictor detects candidate targets for specific immune responses to Monkeypox virus (H/T @harisankars1)
https://t.co/yjTcjYxSGN?

[Roland Baker @RolandBakerIII]

Intentions to get vaccinated against Monkeypox in Healthcare workers in France and Belgium correlates with attitudes toward COVID-19 vaccination (h/t @harisankars1)
https://t.co/2mbPGSTKhK

[Roland Baker @RolandBakerIII]

A35R and H3L are Serological and B Cell Markers for Monkeypox Infection (H/T @harisankars1)
https://t.co/Vuu4h49OyL

[Roland Baker @RolandBakerIII]

Modelling vaccination and control strategies of outbreaks of monkeypox at gatherings: Gathering events can be made safe with some restrictions of either the number and density of attendees in the gathering, or vaccination requirements. (H/T @harisankars1)
https://t.co/vq4Uj9Rrlu

[Roland Baker @RolandBakerIII]

Heat inactivation of the Monkeypoxvirus" Our results showed that MPXV was inactivated in less than 5 min at 70 °C and in less than 15 min at 60 °C" That's 158°F and 140°F respectively. (H/T @harisankars1)
https://t.co/iKpLhHzymk

[Nancy Delagrave @RougeMatisse]

Case of monkeypox detected at camp in Beaver County https://t.co/oyDrzJkNI6

H/T @harisankars1

[Roland Baker @RolandBakerIII]

The YMCA of Pittsburgh said a person infected with monkeypox detected at Camp Kon-O-Kwee Spencer is in quarantine and camp officials are working closely with the health department.
https://t.co/WjdrzX0QF3

[Roland Baker @RolandBakerIII]

Recombination shapes 2022 monkeypox outbreak

This study reports evidence of recombination of monkeypox genome in natural transmission by analyzing six tandem repeats (TRs) among 415 sequences collected between January to July 2022

H/T @harisankars1
https://t.co/8S5e4Ouvs6

[Roland Baker @RolandBakerIII]

(1/n) Clinical features, hospitalisation and deaths associated with monkeypox: a systematic review and meta-analysis: A total of 19 articles were included, using only 12 articles in the quantitative synthesis (meta-analysis). (H/T @harisankars1)
https://t.co/Aj1v2tQZ3M

[R P Shah Memorial Trust for Kids & Global Health @Rpshahmemorial1]

In 1975, 3-yr-old Rahima was isolated at home with house guards posted 24 hours a day. A house-to-house vaccination campaign within a 1.5-mile radius & physical check in every house,school & healer within 5 miles done & we let #monkeypox to spread, such a waste of efforts 🤦‍♂️#CDC

[Roland Baker @RolandBakerIII]

Estimation of monkeypox spread in a non-endemic country considering contact tracing and self-reporting: a stochastic modeling study (H/T @harisankars1)
https://t.co/cBYxDsPgf5

[Roland Baker @RolandBakerIII]

Portable nucleic acid tests for rapid detection of monkeypox virus: The assays use loop-mediated isothermal amplification (LAMP) to amplify two distinct sequences in the MPXV genome. (H/T @harisankars1)
https://t.co/25Stqnws9T

[Roland Baker @RolandBakerIII]

(1/n) Bloomberg: Most of Africa’s Monkeypox Cases Are From Household Transmission
* WHO points to proportion of women with the infectious disease
* Majority in regions that have previously reported monkeypox
(H/T @harisankars1)
https://t.co/Ghx7yVPj1v