Congrats to @hasan_hamam on his first author publication in #JCC@OUPAcademic which demonstrates UC patients who enter clinical trials using steroids have:
โฌ๏ธAEs compared to those not using concomitant steroids
โฌ๏ธAEs if not able to attain steroid-free CR (OR 4.5!)
The TRIUMPH study is now published in Crohns Colitis 360 @IBDJournals. Thank you to @CIRC_CCRM for their endorsement, the investigators, and the patients for their participation. Another step to understand use of JAK inhibitors in acute severe UC!
https://t.co/3oX9oljJie
Time to stop lumping together all patients with prior biologic 'exposure'? Our latest work in #JCC@OUPAcademic
found outcomes of IBD patients with prior biologic intolerance to be better than those with prior failure.
https://t.co/8AmxkQqVSd
Now in @AmJGastro: Achieving resolution of rectal bleeding in acute severe UC in associated with 6 months steroid-free clinical remission and endoscopic improvement. Finally a pragmatic patient-reported treatment target for acute severe UC! https://t.co/rF1RdD89jp
โItโs one thing for sarin gas to be used on people in far away Syria who are Muslim and of a different culture. What is Europe going to do when it is on European soil, done to Europeans?โ
Unbelievable from Julia Ioffe on CNN.
If your doctor doesnโt explain the mechanism of each medication youโre on by scribbling a series of alpha helices and phospholipid bilayers and explaining which chemical groups on the drug molecule bind to which amino acid in the target binding site, then simply find a new doctor