Top Tweets for #APN01
LSI Paper of the Day☀️
Evidence builds for #APN01, a soluble recombinant form of human #ACE2 as a potentially universal treatment for #COVID19.
This @EmboMolMed study led by Dr. Josef Penninger showed the drug neutralized infection in all tested #SARSCoV2 variants of concern.

📢Clinical grade #ACE2 as a universal agent to block #SARSCoV2 variants
By G. Wirnsberger, J. Penninger & colleagues @karolinskainst @invIOs_com @IMBA_Vienna @ubclifesciences
👉Fully #openaccess: https://t.co/PpZCiJJAOc

An international team led by #UBC's Dr. Josef Penninger & @karolinskainst's Dr. Ali Mirazimi has shown proof of principle that drug candidate #APN01 is effective against infection with the #Omicron variant.
https://t.co/YJnujlk66H
@apeironbio
@IMBA_Vienna
@IBECBarcelona

The #JosefPenninger drug #APN01 results were supposed to be out by now. (February 25, 2021) That they haven't been released yet and that he has chosen a different topic for an upcoming lecture at Oxford... gives me the impression that the results are not favorable.
@devisridhar If anything, this underscores the need for fundamental therapies built on decades of research. Example: Assuming ACE2 is still the primary receptor, use ACE2 as a decoy... as tested in Phase II trials... with #JosefPenninger's #APN01.
#APN01, el Fármaco Que Bloquea la #COVID19 . Apeiron CEO Llewellyn-Davies: "Wir Brauchen Ein Medikament". Es Capaz de Unirse a la Proteína de Pico del #Virus y Neutralizarlo ... Capaz de Reducir la Carga Viral en Pulmones, Riñones y Corazón https://t.co/FXKBzFAdHy @ccarballo50

#PressRelease Our patient recruitment of our ongoing #phase2 clinical trial with #APN01 a recombinant form of #ACE2 to treat #COVIDー19 is completed.
https://t.co/TLK4v8cui1
#COVID19 #Covid19Treatment #treatment #SARSCoV2

#KarolinskaInsitutet (The place where Renin was discovered.) "Promising results from in vitro combination therapy against COVID-19", November 17, 2020: https://t.co/MCXias8ZMc #Remdesivir #APN01
Great kick-off of the iCA seminar series with an excellent talk by Josef Penninger one ACE2 and Covid-19! @UBC #APN01 @tuBraunschweig

Warum Hoffnung auf streng geprüfte #SARSCoV2-#Impfstoffe zum Jahreswechsel & #Penninger-#COVID19-Arznei #APN01 (Daten zu Weihnachten, danach Notzulassung) berechtigt ist. Ansporn z. Durchhalten - mit Schutz durch Abstand, permanenten #MNS indoor & Hygiene.
https://t.co/CNHEHwtxsS
#JosefPenninger #APN01 November 3, 2020: "Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID19" by Tarek Mohamed Abd El-Aziz, Ahmed Al-Sabi, et al: https://t.co/aYU73GPoMm
@corinnamilborn Was ist mit dem Medikament von Herrn Penninger? #APN01 Hilft es und wann kommt es. Danke!
Dr. Zoufaly on the case study of a hospitalized patient with severe #COVID19 using #Apeironbio soluble rh #ACE2 (#APN01) in a named patient use case. #SARSCoV2 #treatment
Learn more about a case study that discusses a hospitalized patient with severe #COVID19
https://t.co/5v6QE0QKBE
Very promising! #APN01, our soluble human recombinant #ACE2 in phase 2 development may have contributed to the total recovery of a very severe #COVID19 patient. #casereport via @LancetRespirMed
Demiurge AI-based #COVID19 #clinicaltrials outcome predictions put to the public test (186_2020):
SUCCESS for
#APN01 / NCT04335136 / @apeironbio
@BhadeliaMD You're the expert. But IF he becomes critical, I would not hesitate to get him on Recombinant Human ACE2 (or #APN01)... Proven safety in prior trials. A "decoy strategy" that mops up the viral load. Currently undergoing Phase II double blind. Compelling compassionate use case.
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