Top Tweets for #ASIC3
Proprioceptors, though non-nociceptive, express ASIC3 and mediate acid-induced hyperalgesia, linking them to #sngception in both mice and humans 🐁 🚶♀️ 🚶♂️ #Proprioception #ASIC3 https://t.co/EJ1Bzthf67
Polyunsaturated fatty acids (PUFAs) modulate ASIC3 by preventing phospholipid pore block, boosting maximal current. This study reveals a novel mechanism of PUFA-induced ion channel modulation. #PUFAs #IonChannels #ASIC3 @OlemissBMS @olemisspharmacy
https://t.co/Q3c0bAvzzR
Beautiful structures & work by Ananchenko & @MariaMusgaard on #ArachidonicAcid binding & modulation of #ASIC1 & #ASIC3 #ionchannels.
#ephys #electrophysiology #patchclamp #moleculardynamics #structuralbiology
In @JGenPhysiol, Ananchenko & @MariaMusgaard use multiscale MD simulations to predict an outer leaflet PUFA-binding region on the ASIC protein transmembrane domain, building on existing functional data & supporting direct interactions of PUFAs w/ ASICs https://t.co/l1aP2TtJf7
3/10 💠Acid-sensing ion channel 3 (#ASIC3): An analgesic target💠
from Dulai, St. John Smith @psalmotoxin & Rahman @RahmanLab
➡️ https://t.co/8sUPYm1yp1
A very nice review on the physiopathology of #ASIC3 #ionchannels, its role in #pain signaling and its potential as drug target by Ewan St. John Smith @psalmotoxin, Taufiq Rahman @RahmanLab and Jasdip Singh Dulai ➡️ https://t.co/51Otk4mYO2
#ArticlesInPress Functional knock out of ASIC3 attenuates the exercise pressor reflex in decerebrated rats with ligated femoral arteries
https://t.co/uZigru1wT9
@PennStHershey
#exercise #ASIC3 #PeripheralArteryDisease
#末梢皮膚細径線維受容器活動 を#単一神経記録法 により体系的に記録・解析したところ、FMモデルでは、#機械感受性C線維侵害受容器の割合が有意に低下していた。
引用元
https://t.co/sBO9Ahtx7f
#線維筋痛症
#ガガFibromyalgia https://t.co/BnIvOzm8Zj
線維筋痛症にもバイオマーカーができますように✨ https://t.co/8jZ8O1oUC7
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